Site Name:
Belgium-Rixensart

Posted Date:
Apr 4 2024

Job Purpose:

Your Responsibilities:

• You will be expected to lead autonomously the development of bacterial or yeast based fermentation of antigens (proteins, polysaccharides, Toxins), driving implementation of latest industry trends and stateoftheart technologies into current manufacturing processoxinses, identifying and promoting opportunities for improvements aiming for scalable, high efficiency, robust, and costeffective manufacturing processes with reducedfootprint
• You will be expected to have strong project management skills and perform timeline and resource planning estimations, design development strategies, plan experimental protocols, lead horizontally a team of technicians and operators to execute them, having a strong presence in the lab to ensure best practices, compliance with documentation practices and EHS standards
• You will be expected to follow the Quality by Design approach to process development, leading multidisciplinary Technical Risk Assessments and ensuring to meet all documentation deliverables required at each of the project stage gates
• You will be expected to support the Development Unit Head in bringing the team (both in your own development unit as well as in the others across the department) to the next level in technical knowledge and best practices, proactively promoting initiatives
• You will ensure a strong interface and knowledge sharing with, Manufacturing Science and Technology, manufacturing strategy, site management, Process Science, and engineering departments for building related activities such as revamping, scalingup or tech transfer to new facilities.
• You will work very closely with the Scaleup team from the development stages to ensure smooth transition throughout the scales required at the different project phases,
• You will closely collaborate with the In-Process Analytical organization (IPA) to develop IPA strategy and implement IPA testings as fit for upstream processes.
• You will build strong relationships and a collaborative network with the DS organizations in Italy and US aimed at increasing sharing and learning, better decision making, stimulating people development and pushing top science & technology throughout the network.
• You will be expected to write and review project reports including process history files, process development reports, etc

Why You?

Basic qualifications:

• Master in bioengineering, biochemistry, biotechnology, chemistry or equivalent.
• You already have a first experience in Upstream Drug Substance Development and/or Manufacturing in biopharma/ biotech industry.
• You are motivated by process development from flask to pilot scale fermentor. You can act as a leader both in the lab and management of a small team technician You have a deep interest in technical aspects of the job and you are willing to participate actively on the shopfloor.
• You are knowledgeable in process development of recombinant proteins and viral vaccines based on different type of Hosts.
• You have basic understanding of and statistical approach and models of development as well as Quality by Design
• Critical thinking and problemsolving skills.
• Ability to work in a dynamic multidisciplinary environment
• Ability to embrace changes positively and adapt.
• Strong communication skills.
• Demonstrated ability to be proactive, take initiative, and lead autonomously
• Imprinted with a desire for excellence.
• Optimistic and openminded.
• Fluent in spoken and written English scientifically/technically as well as conversational are a MUST.
• Being able to communicate in French or willing to learn.

Preferred qualifications:

• Ideally a first experience in fermentation or cell culture in research or manufacturing, particularly in bacteria and yeasts expression systems.
• A good understanding of clinical and commercial Manufacturing processes and Manufacturing constraints.
• A good understanding and knowledge of process industrialization methods.
• Understanding in continuous manufacturing, Systems Biology (omics), big data, multivariate analysis, predictive analytics and modelling approaches.

Li-GSK

If you have a disability and require assistance during the course of the selection process, you will have the opportunity to let us know what specific assistance you require in order to make suitable arrangements.

Why Us?

GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organization where people can thrive.

Getting ahead means preventing disease as well as treating it, and we aim to positively impact the health of 2.5 billion people by the end of 2030.

Our success absolutely depends on our people. While getting ahead of disease together is abo

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