Postdoctoral scientist: Implementation of chrononutrition to tackle circadian disruption in the intestine of patients with obesity

il y a 4 semaines


Leuven, Belgique KU Leuven Temps plein
PhD in biomedical sciences, bioengineering, biotechnology, pharmaceutical sciences, nutrition or related fieldStrong interest in fundamental mechanisms of diseaseGood academic performance at MSc and PhD levelPublished articles as first authorProficiency in written and spoken EnglishCreative with a strong interest in innovationAble to integrate in an international working environmentDesign and execute high-quality experimentsHelping with data interpretation and playing a key role in publication of project resultsClosely collaborate and supervise PhDs, technicians and master students involved in the projectCommunicate research findings within the European consortium and at international meetings The Gut Peptide Research lab is recruiting a postdoctoral scientist to perform research in the framework of a European Horizon project SHIFT2HEALTH. This project investigates how shift-work related diseases such as obesity disrupt the cross-talk between circadian clocks and metabolic pathways in the gut that regulate homeostasis. We aim to study in human organoids how intermittent fasting or chronobiotics can restore this circadian misalignment which results in adverse health effects. Our research integrates state-of-the-art techniques ranging from RNA-sequencing to super resolution imaging and metabolic studies in 3D intestinal organoids obtained from obese patients. The lab is integrated within the Translational Research Center for Gastrointestinal Disorders (TARGID) at KU Leuven (www.targid.eu) and benefits from the basic and clinical expertise within TARGID to implement top quality research in the field of gastroenterology, endocrinology and nutrition. This research project involves collaborations across multiple centers, and will provide opportunities for the candidate to broaden their network and to gain experience in translational research. The laboratory is strongly international and the university offers a stimulating environment for researchers to achieve their ambitions and to plan their career development. Excellent guidance by a dynamic multidisciplinary teamSupport to submit and lead research proposalsHigh level scientific training in a top-ranked universityA 3-year position, with an initial contract of 1 yearA challenging job in a dynamic and international environmentStarting as soon as possible


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