Powder Scientist
il y a 1 jour
Brainel'Alleud, Belgique
Jefferson Wells
Temps plein
Contracting – Walloon BrabantJob description As a “scienassionate” person and Powder Scientist you like to work in an environment where you can:
- Participate to the development of new products and processes
- Give directions from early development up to lifecycle management, from particle design up to final product
- Work autonomous, well-organized and use your pro-active thinking skills
- Be self-reflective on the gathered data
- Use your creativity to develop new analytical methods or even develop new technology
- Drive team spirit and encourage collaboration
As a “scienassionate” person and Powder Scientist you will contribute by:
- Being a leader in powder characterization by leveraging Materials Science to drive overall Product Development in order to obtain the right drug for every patient
- Guide the Product Development by connecting powder /particle insights with manufacturing technologies and overall product performance
- Combine particle knowledge with crystallization science to optimize expected powder properties
- Developing method and performing analyses on active ingredient, drug product and excipients in the field of powder characterization
- Independently planning, conducting and interpreting experiments to determine the bulk powder and particle properties of raw materials, intermediates and final dosage forms, by mastering a number of characterization tools: laser diffraction (wet and dry method) and microscopy (optical and SEM) for particle size and shape measurements; gas pycnometry and fine solid displacement methods for true and envelope density determinations; physisorption for surface area quantification and porosimetry; powder rheometry to assess powder flow stability and strain-rate dependency; shear cell testing to measure powder flow functions and wall friction with application to hopper design; surface energy and wettability analyses via contact angle measurements (sessile drop, Washburn and Wilhelmy plate methods), standardized and customized methods to evaluate bulk/tapped density, powder compressibility, permeability, mechanical strengths of tablets and/or agglomerates, electrostatic charging, segregation, sticking and caking propensity; dynamic vapor sorption to assess powder hygroscopicity; differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) to understand the powder thermal behavior.
- Performing chemical imaging on drug product or intermediates
- Being the reference person in powder characterization and training colleagues
- Applying QbD principles, multivariate analyses, and being in support of PAT development
- Keeping track of literature and state of the art scientific practices, and implementing innovative solutions
- Communicating with stakeholders and external partners (universities, centers of expertise,..)
- Writing reports and give internal and external presentations
- Master / PhD in chemistry, pharmaceutics, physics or engineering or equivalent experience, on powder characterization
- Fluent in English
- Ability to work at the interface
- Able to combine multiple tasks and work simultaneously on different projects
- Soft skills: entrepreneurship, motivated, enthusiastic, reliable, team player, good communication
You’re interested in this job? We kindly invite you to apply. Do you have any questions? You can contact Caroline, caroline.michon@jeffersonwells.be
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Powder Scientist
il y a 2 jours
Braine-l'Alleud, Belgique Jefferson Wells Temps pleinContracting – Walloon Brabant As a “scienassionate” person and Powder Scientist you like to work in an environment where you can: Participate to the development of new products and processes Give directions from early development up to lifecycle management, from particle design up to final product Work autonomous, well-organized and use your...
