DMPK Lead

il y a 6 jours

Bruxelles, Région de Bruxelles, Belgique RBW Consulting Temps plein

RBW are working in partnership with a global organisation that are searching for an experienced DMPK Lead to implement strategy across all DMPK disciplines including PK/PD, ADME, Biotransformation etc. from early discovery through to clinical development.

Responsibilities:

  • Lead the nonclinical DMPK strategy and design the appropriate studies to fulfil regulatory requirements
  • Have an expert understanding of the different approaches related to nonclinical pharmacokinetics
  • Apply understanding of physical properties, DMPK and enzymology to contribute to the design of new compounds
  • Work with colleagues globally to resolve project-related ADME challenges
  • Author high quality regulatory documents including INDs, CTAs and NDA filings

Experience:

  • Educated to PhD in a scientific related discipline
  • Minimum 5 years industry experience contributing to drug discovery projects with a track record of moving small molecules from target validation to first in humans
  • Strong background in the area of DMPK/ADME across discovery and development
  • Good understanding of PKPD and PBPK modelling
  • Proven skills for in-depth mechanistic understanding of DMPK-related issues and of the impact and value of translation to humans

  • DMPK Expert Leader

    il y a 5 jours

    Bruxelles, Région de Bruxelles, Belgique RBW Consulting Temps plein

    RBW Consulting is working in partnership with a global organisation to implement strategy across all DMPK disciplines, including PK/PD, ADME, Biotransformation and more.Key Responsibilities:Develop and lead the nonclinical DMPK strategyDesign studies to meet regulatory requirementsPursue expert knowledge of pharmacokinetic approachesContribute to the design...

  • Senior Nonclinical Pharmacokinetics Specialist

    il y a 5 jours

    Bruxelles, Région de Bruxelles, Belgique RBW Consulting Temps plein

    Rewarding opportunity to join RBW Consulting and drive strategic initiatives in nonclinical pharmacokinetics.About the Role:Lead the nonclinical DMPK strategy across multiple disciplinesDevelop and execute studies to satisfy regulatory needsMaintain deep expertise in pharmacokinetic methodologiesApply physical property and enzymology knowledge to compound...