Senior/principal Scientist

At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented, treated, and cured,where treatments are smarter and less invasive, andsolutions are personal.Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.Learn more at jnj.com.

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Pharmaceutical Product R&D

Job Category:

Scientific/Technology

All Job Posting Locations:

Beerse, Antwerp, Belgium

Job Description:

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

Within Johnson & Johnson Innovative Medicine, we are recruiting a Senior/Principal Scientist with strong skills in High-resolution mass spectrometry – based structure elucidation and an emphasis on complex synthetic modalities, such as antibody-drug conjugates and targeted lipid nanoparticles (tLNPs).

Johnson & Johnson Innovative Medicine develops treatments that improve the health and lifestyles of people worldwide. Our development areas encompass novel targets in neurologic disorders, gastroenterology, oncology, infectious disease, diabetes, hematology, metabolic disorders, immunologic disorders, pulmonary hypertension and reproductive medicine. The successful candidate will be employed in our Analytical Development (AD) organization, responsible for Global Therapeutics Development and Supply (TDS) Organization.

The (Senior) Scientist will join the Advanced Material's Characterization and Investigations (AMCI) group within AD. AMCI is an international and diverse, multidisciplinary team of scientists leading advanced characterization and mechanistical understanding of our drug substances and drug products. We are also leading analytical investigations for commercial and R&D portfolio.

Within AMCI, the Advanced Molecular Analysis (AMA) team is a group of analytical centers of excellence in structure elucidation (by high-resolution mass spectrometry and NMR), organic and inorganic trace analysis, polymer characterization, and Antibody-drug conjugate (ADC), oligonucleotide & peptide analytics as well as analytical support for the development tLNPs

We are currently seeking a skilled and enthusiastic Scientist with a strong background in High-resolution mass spectrometry on diverse therapeutic modalities to strengthen our AMA team. In this team, you will play a crucial role the identification of process impurities and degradation products of our diversifying synthetic molecule portfolio. This laboratory-based position offers you the opportunity to lead the development, implementation, and execution of innovative analytical test methods for several types of complex, synthetics active pharmaceutical ingredients like (cyclic) peptides, oligonucleotides, ADCs as well as tLNP constituents (mAbs, mRNA lipids,…). In this role, you will also collaborate closely with internal and external specialists to conduct thorough root–cause investigations and explore innovative approaches for optimal analyses and characterization. If you are passionate about pushing the boundaries of analytical techniques and eager to make a significant impact in the field, we would love to hear from you

The position is based in Antwerp (Beerse), Belgium.

Key Responsibilities:

• Design and develop advanced (High Resolution) Mass Spectrometry-based methods for structure elucidation of diverse active pharmaceutical ingredients, with a emphasis on complex pharmaceutical modalities like ADCs and targeted lipid nanoparticle (tLNPs) components.
• Take the lead in the development of a comprehensive analytical toolbox for characterization of complex active pharmaceutical ingredients.
• Apply state-of-the art scientific knowledge to ensure high quality of the delivered results.
• Work in a multidisciplinary team of scientists and show the ability to learn and explore new analytical techniques.
• Maintain a safe work environment in compliance with all