Postdoctoral Researcher in Stem Cell Biology and Early Human Development

Il y a 2 jours

Louvain, Vlaams-Brabant, Belgique Karlstad University Temps plein 38 000 € - 58 000 € Contrat

Select the region that best fits your location or preferences.

This setting controls the language of the user interface, including buttons, menus, and all site text. Select your preferred language for the best browsing experience.

Select the languages for job listings you want to see. This setting determines which job advertisements will be displayed to you.

Swedish

Norsk

Danish

Finnish

German

French

Dutch

Spanish

Job Match Comparison

Compare your profile with the job requirements

Job or profile information is not available.

Why this job matches your profile

We've compared your profile to the job requirements. Here's where they align.

Job or profile information is not available.

You have already applied for this position.For questions regarding your application, please contact the employer.For technical assistance, reach out to our support teamhere .

Thank you for your application An email confirmation has been sent to your email.

Loading job alert...

Receive job alerts that match your preferences.

Select employers Search and select specific employers to receive job alerts only from them.

Postdoctoral Researcher in Stem Cell Biology and Early Human Development

KU Leuven is an autonomous university. It was founded in 1425. It was born of and has grown within the Catholic tradition.

The Pasque lab is dedicated to understanding how early human development, pluripotency, and epigenetic processes are regulated, with the ultimate goal of advancing reproductive and regenerative medicine.
Recent publications from the group: Van Knippenberg et al. bioRxiv 2026, Panda et al. bioRxiv 2025, Allsop et al. Nat Comm 2025, Shahbazi and Pasque Cell Stem Cell 2024, Pham et al. Cell Stem Cell 2022, Zijlmans et al. Nature Cell Biology 2022, Posfai et al. Nature Cell Biology 2021.
Our mission is to unravel the mechanisms governing cell fate decisions, gene regulation, and chromatin dynamics during early mammalian development. To achieve this, our team employs a diverse toolkit including stem cell-based embryo models, blastoids, genetic, molecular, cellular, and computational approaches to investigate the regulatory circuits orchestrating peri-implantation development and pluripotency, aiming to uncover molecular alterations that contribute to human health and disease.
The Pasque lab is part of the Faculty of Medicine, Department of Development and Regeneration, embedded in the stem cell and development cluster, and is affiliated with the Leuven Single-Cell Omics Institute.

The Pasque lab is seeking a highly motivated postdoctoral scientist to join a project dedicated to decoding early human embryo development through cutting-edge stem cell-based embryo models, single-cell omics, with a focus on cell fate and epigenetics.
This project is conducted in close collaboration with the laboratory of Dr. Claire Rougeulle (Curie Institute, France), Dr. Laurent David (University of Nantes, France) and Dr. Thierry Voet (KU Leuven) and other leading researchers in the field.

The project aims to elucidate the gene regulatory networks underlying early human postimplantation development, with a particular focus on the mechanisms of cell fate specification in extraembryonic lineages, as well as X-chromosome inactivation. Using innovative stem cell-based embryo models such as blastoids, CRISPR perturbations, microscopy and single-cell omics, the researcher will use and develop stem cell-based embryo models and uncover fundamental processes for human development and reproductive health.

  • Develop and apply stem cell-based embryo models to investigate cell fate transitions and epigenetic processes, including X-chromosome inactivation.
  • Generate and analyze microscopy and single-cell (multi)omics datasets.
  • Participate actively in postdoctoral training and career development activities, including scientific publishing, grant writing, leadership development, networking, and career planning.

Profile

  • Strong publication record in peer-reviewed international journals.
  • Demonstrated expertise in mammalian stem cells, gene regulation, and molecular techniques.
  • Prior experience in cell culture, molecular biology, transcriptomics, epigenomics, early mammalian embryogenesis, human pluripotent stem cells, epigenetics, X-chromosome inactivation, embryo models, microscopy, RNA FISH, single-cell genomics and computational biology is an advantage.
  • Strong enthusiasm for collaborative interdisciplinary research in early human development.

Offer

  • A competitive salary according to KU Leuven standards.
  • An initial appointment of one year with the possibility of extension up to three years based on performance and funding availability.