PhD Research Scientist

Scientist Employment Status:Full Time
Company Division:R&D
Head of Laboratory Operations
Today, precision medicine coupled with advanced diagnostics is taking over. However, those innovations in medicine come with an ever-increasing price tag driven by more expensive and complicated solutions making them less accessible unless we do something about it.
As a startup we have developed a technology to profile complex molecular signatures in a single reaction using qPCR machines already in place in every biomedical lab around the world. Signatur Biosciences is a startup with a remote workforce, predominantly in London, UK, and is establishing a new laboratory facility in Liège, Belgium.
We're worried about accessibility in precision diagnostics and are building a team of individuals who share our passion for solving this problem through close collaboration and a sense of urgency. We're building a different kind of company, where employees think like owners, act with authority, and collaborate closely with one another.
We are seeking a highly motivated and driven Scientist to join our team to help establish our new Belgium laboratory facility (full time, on site). In this role, under the direction of the Head of Laboratory Operations, you will be responsible for ensuring the timely and accurate planning, documenting and execution of laboratory studies to support the development of innovative diagnostic products. You will be part of an expanding laboratory operations team but also interact with colleagues across the company who have the shared mission to make precision diagnostics more accessible. If you are a highly motivated and driven self-starter with a passion for novel diagnostics development, we'd love to speak with you
As a Scientist, you will be responsible for ensuring the efficient and effective translation of project objectives into detailed and accurate protocols and work instructions. You will play a crucial role in advancing innovative diagnostic solutions by performing molecular biology techniques, analyzing experimental data, and ensuring the highest standards of quality and accuracy. Your contributions will directly impact the success of cutting-edge qPCR-based diagnostic kits, while collaborating with a dynamic and interdisciplinary team.
Responsible for adherence to laboratory procedures to ensure a safe and effective laboratory environment
Be responsible for the work instructions and training for specific laboratory processes/equipment as a lab process expert
Contribute to the laboratory processes / procedures implementation in accordance with In Vitro Diagnostic development (ISO13485)
Support the Head of Laboratory Operations in the implementation and monitoring of metrics (Key Performance Indicators) of laboratory efficiency & effectiveness
Training and coaching of laboratory team members
Ensure the efficient translation of study plans and protocols into detailed laboratory work instructions/worksheets to enable laboratory execution
Work across the R&D team to anticipate reagents and consumable needs
Take ownership of data analysis and report writing
Train the laboratory team on the study protocols/work instructions
Conduct laboratory studies in accordance with work instructions and/or study protocols in support of research and/or product development projects including:
Execute laboratory studies with a 1st time right mentality, leading by example
Document experiments according to the Quality management System requirements ensuring timely, neat, complete and accurate records
Recognized as Subject Matter Expert in diagnostic research, development and/or manufacturing
Proven track record in planning and writing study protocols and work instructions
Proven track record of timely and accurate laboratory record keeping
Experience in working collaboratively and coordinating laboratory activities
PhD, Master or equivalent Science degree in biology, molecular biology, synthetic biology, bioengineering, or similar, with equivalent experience.
At least 3 years of hands-on molecular biology laboratory experience (not including course work)
Experience working within a Quality Management System for In Vitro Diagnostic development (ISO13485)
Familiarity with a scientific programming language (Python, R, Matlab or Julia)
Fluent in English & French
Experience in writing study protocols following relevant international guidelines (i.e. Mentoring and/or coaching team members
Planning and Problem Solving
Private medical insurance
We do not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender (including gender identity and gender expression), sex (which includes pregnancy, childbirth, and breastfeeding), genetic information, taking or requesting statutorily protected leave, or any other basis protected by law.

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