Senior Technical Assistant

il y a 2 semaines


Liège, Wallonie, Belgique Signatur Biosciences Temps plein

Job Title:Senior Technical Assistant

Employment Status:Full Time

Company Division:R&D

Location: Liège, Belgium

Salary:Competitive

Reporting into: Head of Laboratory Operations

About Signatur Biosciences

Today, precision medicine coupled with advanced diagnostics is taking over. However, those innovations in medicine come with an ever-increasing price tag driven by more expensive and complicated solutions making them less accessible unless we do something about it.

Signatur Biosciences was established with the mission of making cutting-edge diagnostic tools accessible to more patients around the world. As a startup we have developed a technology to profile complex molecular signatures in a single reaction using qPCR machines already in place in every biomedical lab around the world. Signatur Biosciences is a startup with a remote workforce, predominantly in London, UK, and is establishing a new laboratory facility in Liège, Belgium.

We're worried about accessibility in precision diagnostics and are building a team of individuals who share our passion for solving this problem through close collaboration and a sense of urgency. We're building a different kind of company, where employees think like owners, act with authority, and collaborate closely with one another.

We are seeking a highly motivated and driven Senior Technical Assistant to join our team to help establish our new Belgium laboratory facility (full time, on site). In this role, under the direction of the Head of Laboratory Operations, you will be responsible for developing, implementing and maintaining all necessary procedures and process required for a state-of-the-art ISO13485 compliant laboratory facility and for the generation of data to support the development of next generation molecular diagnostic products. You will join Signatur Biosciences at an exciting time as we are a small start-up company looking to grow. You will be part of an expanding laboratory operations team but also interact with colleagues across the company who have the shared mission to make precision diagnostics more accessible. If you are a highly motivated and driven self-starter with a passion for novel diagnostics development, we'd love to speak with you

About the role

As a Senior Technical Assistant, you will be responsible for ensuring the efficient and effective operations of the laboratory by performing regular maintenance, laboratory housekeeping activities and coordinating the activities of team members. You will also be responsible for the execution and recording of laboratory experiments in accordance with specified work instructions and protocols.

Main Responsibilities

People and Laboratory Operations

  • Assist the Head of Laboratory Operations with the planning, supervision and coordination of laboratory activities.
  • Responsible for ensuring a safe and effective laboratory environment through completion of daily maintenance and housekeeping activities
  • Maintain and calibrate laboratory equipment
  • Order & receive laboratory supplies, equipment and apparatus
  • Assist in the storage, handling and maintenance of records with regards biological samples in accordance with the relevant requirements
  • Be responsible for work instructions, training and maintenance of specific laboratory processes/equipment as a lab process expert
  • Contribute to the laboratory processes / procedures implementation in accordance with In Vitro Diagnostic development (ISO13485)
  • Support the Head of Laboratory Operations in the implementation and monitoring of metrics (Key Performance Indicators) of laboratory efficiency & effectiveness
  • Contribute towards the continuous improvement of the laboratory facility and operations of Signatur Biosciences
  • Training and coaching of team members

Project and Product Delivery

  • Conduct laboratory studies in accordance with work instructions and/or study protocols in support of research and/or product development projects including:
  • Performing qPCR experiments manually or using high-throughput liquid handlers (for example i.DOT machine)
  • Carry out nucleic acid extractions according to specified protocols or work instructions
  • Execute laboratory studies with a 1st time right mentality, leading by example
  • Document experiments according to the Quality management System requirements ensuring timely, neat, complete and accurate records
  • Contribute to, and where necessary take the lead in, trouble shooting and investigations of unexpected laboratory results
  • Communicate effectively with all stakeholders to ensure practical laboratory considerations are incorporated into study planning
  • Assist in coordinating the simultaneous delivery of multiple laboratory studies within, and across, projects

Technical Expertise

  • Expert in PCR
  • Experience with nucleic acid extraction
  • Experience with maintenance and calibration of laboratory equipment
  • Experience of timely and accurate laboratory record keeping
  • Experience in coordinating laboratory activities

Skills, Experience & Attributes

Essential Skills/Experience

  • Bachelor of Science degree in biology, molecular biology, synthetic biology, bioengineering, or similar
  • At least 3 years of hands-on molecular biology laboratory experience (not including course work)
  • Fluent in English & French

Desirable Skills/Experience

  • Previous start-up or diagnostic industry experience
  • Experience in using automated PCR set-up instruments
  • Knowledge in the field of molecular diagnostics
  • Familiarity with a scientific programming language (Python, R, Matlab or Julia)
  • Experience of working within biobanking requirements
  • Experience in laboratory supervision of staff
  • Experience working within a Quality Management System for In Vitro Diagnostic development (ISO13485)

Key Competencies

  • Planning and Problem Solving
  • Sense of Urgency and Focus
  • Team work and communication

Compensation and Benefits at Signatur Biosciences include:

  • Competitive Base Salary (compensation will be based on experience level with requested qualifications).
  • Paid time off policy that includes: 4 weeks, 12 compensatory days and approximately 3 - 5 additional days during year-end holidays.
  • Private medical insurance

As we continue to grow, our benefits package will evolve. The benefits outlined above are accurate as of the job posting date.

Signatur Biosciences is an equal-opportunity employer promoting diversity and inclusion in the workspace. We do not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical conditions, veteran status, sexual orientation, gender (including gender identity and gender expression), sex (which includes pregnancy, childbirth, and breastfeeding), genetic information, taking or requesting statutorily protected leave, or any other basis protected by law.


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