(Senior) Research Associate Confobody® Discovery

il y a 4 jours


Brussels, Belgique Confo Therapeutics Temps plein

For the expansion of the Biologics Discovery team in Confo’s Brussels exploitation site, we are recruiting a (M/F):
**(Senior) Research Associate ConfoBody Discovery**

**Your responsibilities**:

- You will assist in developing innovative flow cytometry based ConfoBody discovery techniques to GPCRs across target programs.
- You will clone VHH antibody repertoires, execute antibody selections by single cell sorting and characterize antibodies using a broad span of biochemical and cell-based assays to assess their conformation sensitivity.
- You will clone and express membrane proteins in mammalian cells using a variety of transformation methods.
- You communicate experimental progress to the project team(s).
- Degree of Bachelor or Master in Industrial Sciences (Industrial Engineer), Biochemistry, Biotechnology or equivalent. Bench oriented and preferentially trained in an industry environment (biotech or pharma).
- Robust hands-on experience with mammalian cell culturing and cell transformation (transient or stable cell line generation). Direct experience with lentivirus enabled transduction of mammalian cells or reporter assays is desired.
- Hands-on experience with state-of-the-art cloning techniques and RT-qPCR.
- You’d like to become best friends with the flow cytometer: capable to independently operate, acquire and analyse data.
- Skilled in _de novo_ antibody discovery to membrane protein targets via antibody display is an asset.
- Self-motivating and problem-solving team member.
- Excellent communication skills in English. Communicates research results (cross-) teams.

***:
**Our offer**:

- A competitive compensation package with extensive benefits.
- An entrepreneurial and stimulating international working environment in a growing and ambitious biotech company.
- Excellent career development opportunities, with exposure to all aspects of R&D in the company.


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