Upstream Group Leader

il y a 6 jours

Brainel'Alleud, Belgique UCB S.A. Temps plein

**Make your mark for patients**

We are looking for an **Upstream Group Leader (Late Stage)** to join us in our **Biologics DS Process Sciences** department, based in **Braine-l’Alleud**, **Belgium**

**About the role**

The Upstream (USP) Group Leader (Late Stage) will be responsible for **providing support for CMC Process Development activities of antibody-based therapeutics** including technology transfer activities enabling drug manufacture.

Please note that we are looking for someone that is going to endorse this role at **Principal Scientist** level.

**Who you’ll work with**:

- Wolfgang Paul (Head of Mid & Late-Stage Process Sciences) as your Manager.
- Your team members composed of 6 Scientists.
- A lot of internal customers (QA, QC, Regulatory Affairs, ) and external partners (CRO’s).

**What you’ll do**:

- Timely and in budget Upstream Process Development across projects.
- Effective recruitment and training concepts for all late-stage process science staff.
- Strive for operational excellence and achieve high success rates for upstream process development, scale down/scale up, technology transfer and Industrialization.
- Drive effective process monitoring, data management and process learning and highlight potential process improvements.
- Efficient characterization of processes.
- Efficient process development of NBE’s.
- Support to UCB’s standard process platforms.
- Participate in the transfer of processes from small scale development units to the pilot plant, MSAT and to commercial manufacturing sites.
- Work closely with the Biologics Pilot Plant and the technology transfer group with regard to platform improvements and ensuring the scalability and manufacturability of production processes.
- Utilize process and laboratory derived data to support technical investigations and aide in process optimization/development.
- Provide an upstream process expert and key point of contact for each assigned externally developed process. Provide guidance and feedback to team members to ensure successful collection and analysis of all existing data and reports relating to assigned projects. Help them perform gap analysis in collaboration with the technology transfer management team. Plan process understanding and characterization activities with a clearly defined scope, required resources and timelines. Effectively communicate those plans to all of those concerned (TST, Management, Downstream Process Development teams, Analytics group etc).
- Supervise and perform daily laboratory activities relating to media making, support cell banking, inoculum and fermentation/cell culture process development and characterization as well as in process analytical methods. Provide technical expertise in matters regarding cell culture process development.
- Author and/or review relevant CMC sections for regulatory filings.
- Author and/or review technical reports, process summaries, protocols, and quantitative analyses. Perform fundamental literature and patent searches related to processes under development.
- Build and maintain effective working relationships with internal customers and external contacts.
- Build and maintain a strong external academic network, peer recognition of highest scientific and technical excellence and strong relationship with regulatory agencies regarding CMC matters.
- Define UCB’s Biologics control strategies for upstream processes.
- Understand the impact of upstream processes on downstream processes and manufacturing facilities.
- Ensure successful validation of processes with a strong understanding of global regulatory requirements.

**I**nterested? For this role we’re looking for the following** **education, experience** **and **skills***
- PhD or master’s degree.
- At least 8 to 10 years of experience within the industry with upstream bioprocessing, particularly late-stage process characterisation and validation, including systematic troubleshooting.

Please note that we are looking for someone that is going to endorse this role at **Principal Scientist** level.
- Proven track record of drug substance commercialization and manufacturing science & technology, technology transfer expertise for monoclonal antibodies.
- Working knowledge of Downstream & Analytics.
- Proven Management and Leadership experience/skills.
- Very good command in English, good command in French is a strong asset.

Are you ready to ‘go beyond’ to create value and make your mark for patients? If this sounds like you, then we would love to hear from you

**About us**
UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 8,500 people in all four corners of the globe, inspired by patients and driven by science.

**Why work for us?**
At UCB, we don’t just complete tasks, we create value. We aren’t afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respec

  • Upstream Group Leader

    il y a 3 semaines

    Braine-l'Alleud, Wallonie, Belgique UCB S.A. Temps plein

    Make your mark for patientsWe are looking for an Upstream Group Leader (Late Stage) to join us in our Biologics DS Process Sciences department, based in Braine-l'Alleud, BelgiumAbout the roleThe Upstream (USP) Group Leader (Late Stage) will be responsible for providing support for CMC Process Development activities of antibody-based therapeutics including...

  • Upstream Tech Transfer Lead

    il y a 3 semaines

    Braine-l'Alleud, Wallonie, Belgique BioTalent Temps plein

    BioTalent are partnered with a global leader in the Pharmaceutical industry to support the hire of a Tech Transfer Lead, specialising in upstream biologics production processes, based in the Walloon region of Belgium.This role will offer you: A pivotal role in the MSAT team, leading Technology Transfers cross functionally whilst leading a team to support PPQ...

  • Msat Upstream Process Transfer Lead

    il y a 3 semaines

    Braine-l'Alleud, Belgique UCB S.A. Temps plein

    **Make your mark for patients** We are looking for a **MSAT Upstream Process Transfer Lead** who is a** leader driven by initiatives and solutions** to join us in our Global Biologics Manufacturing Sciences & Technology (MSAT) Tech Transfer team, based in **Braine-l’Alleud**, **Belgium.** **About the role** The Upstream (USP) Process Transfer Lead is...

  • Upstream Associate Scientist

    il y a 6 jours

    Braine-l'Alleud, Belgique UCB Temps plein

    **Make your mark for patients** We are looking for an **Upstream Associate Scientist** who is **flexible** and **multi-tasking** to join us in our **Biologics DS Process Sciences** department, based in **Braine-l’Alleud**, **Belgium** **About the role** The Associate Scientist within the Upstream Process Sciences Group will be involved in activities...

  • Upstream Associate Scientist

    il y a 3 semaines

    Braine-l'Alleud, Wallonie, Belgique UCB Temps plein

    Make your mark for patientsWe are looking for an Upstream Associate Scientist who is flexible and multi-tasking to join us in our Biologics DS Process Sciences department, based in Braine-l'Alleud, BelgiumAbout the roleThe Associate Scientist within the Upstream Process Sciences Group will be involved in activities relating to the early-stage process...

  • Upstream Associate Scientist

    il y a 3 semaines

    Braine-l'Alleud, Belgique UCB S.A. Temps plein

    **Make your mark for patients** We are looking for an **Upstream (USP) Associate Scientist** who is **flexible, collaborative and multi-task** to join us in our **Biologics Process Sciences** team, based in **Braine-l’Alleud**, **Belgium** **About the role** The position is based in a laboratory environment, and it implies **experiments in bioreactors**...

  • Upstream Associate Scientist

    il y a 3 semaines

    Braine-l'Alleud, Wallonie, Belgique UCB S.A. Temps plein

    Make your mark for patientsWe are looking for an Upstream (USP) Associate Scientist who is flexible, collaborative and multi-task to join us in our Biologics Process Sciences team, based in Braine-l'Alleud, BelgiumAbout the roleThe position is based in a laboratory environment, and it implies experiments in bioreactors going from AMBR15 to 200L scales, in...

  • Upstream Manufacturing LCM Chemist

    il y a 4 semaines

    Braine-l'Alleud, Belgique PolyPeptide Temps plein

    We are looking for a Chemist for our Upstream Manufacturing Life Cycle Management. Nature & Scope: Manage upstream commercial manufacturing products in term of campaigns preparation, follow-up and release with all the associated scientifical /technical aspects in order to assure that the manufacturing products are running according to expectations...

  • Upstream Process Technician

    il y a 1 mois

    Braine L'alleud, Belgique UCB Temps plein

    ​Faites la différence pour les patientsWe are looking for a dynamic and motivated Upstream Process Technician to join our team at the Bio Pilot Plant, located at our site in Braine L’Alleud, Belgium. About the roleAs a Process Technician, your main function will be to produce proteins in the developmental phase, in accordance with...

  • Production Team Leader

    il y a 3 semaines

    Braine-l'Alleud, Wallonie, Belgique PolyPeptide Temps plein

    PolyPeptide Laboratories is a high-tech enterprise specializing in the development, manufacture and sale of therapeutically active peptides . PolyPeptide SA, Belgium, with approximately 320 employees is part of the international PolyPeptide Group with companies in Sweden, India, USA, France and Belgium. To strengthen our Manufacturing Department based...

  • Gene Therapy Downstream Team Leader

    il y a 3 semaines

    Braine-l'Alleud, Wallonie, Belgique UCB Temps plein

    Make your mark for patients Nous recherchons un(e) Team Leader Downstream (FR) pour rejoindre notre département Biologics & Gene Therapy Clinical Manufacturing Sciences , basé sur notre campus de Braine-l'Alleud , Belgique. À propos du rôle Vous jouerez un rôle clé en dirigeant une équipe de techniciens dans notre unité de production de...

  • Msat Usp Senior Scientist

    il y a 4 semaines

    Braine-l'Alleud, Belgique UCB Temps plein

    **Make your mark for patients** We are looking for a Manufacturing Sciences & Technology (MSAT) Lab Upstream Senior Scientist who is dynamic, experienced, and collaborative to join our Global Biologics MSAT team, based at our UCB campus in Braine-l’Alleud, Belgium. **Who You Will Work With** In this global role, you'll work closely with development and...

  • Team Leader

    il y a 3 semaines

    Braine-l'Alleud, Belgique UCB Temps plein

    **Faites la différence pour les patients** Nous recherchons un.e **Team Leader** qui est organisé, fiable, ayant l’esprit d’équipe pour nous rejoindre dans notre équipe de** Bio & Gene Therapy Clinical Manufacturing Sciences**, basé sur notre campus de **Braine-l’Alleud**, **Belgique** **À propos du rôle et ses objectifs principaux** -...

  • Msat Usp Senior Scientist

    il y a 3 semaines

    Braine-l'Alleud, Wallonie, Belgique UCB Temps plein

    Make your mark for patientsWe are looking for a Manufacturing Sciences & Technology (MSAT) Lab Upstream Senior Scientist who is dynamic, experienced, and collaborative to join our Global Biologics MSAT team, based at our UCB campus in Braine-l'Alleud, Belgium.Who You Will Work WithIn this global role, you'll work closely with development and commercial...

  • Team Leader

    il y a 3 semaines

    Braine-l'Alleud, Wallonie, Belgique UCB Temps plein

    **Faites la différence pour les patients**Nous recherchons un.e **Team Leader** qui est organisé, fiable, ayant l'esprit d'équipe pour nous rejoindre dans notre équipe de** Bio & Gene Therapy Clinical Manufacturing Sciences**, basé sur notre campus de **Braine-l'Alleud**, **Belgique****À propos du rôle et ses objectifs principaux**- Participer à la...

  • Media Development Scientist

    il y a 3 semaines

    Braine-l'Alleud, Belgique UCB S.A. Temps plein

    **Make your mark for patients** We are looking for a **Media Development Scientist** who is **team player, proactive and flexible** to join us in our **Upstream Process Sciences** team, based in Braine-l’Alleud, **Belgium** **About the role** The Media Development Scientist within the Upstream Process Sciences Group will be involved in media development...

  • Gene Therapy Downstream Team Leader

    il y a 3 semaines

    Braine-l'Alleud, Wallonie, Belgique UCB Temps plein

    Make your mark for patients Nous recherchons un(e) Team Leader Downstream (FR) pour rejoindre notre département Biologics & Gene Therapy Clinical Manufacturing Sciences, basé sur notre campus de Braine-l'Alleud, Belgique. À propos du rôleVous jouerez un rôle clé en dirigeant une équipe de techniciens dans notre unité de production de thérapie...

  • Gene Therapy Downstream Team Leader

    il y a 1 mois

    Braine-l'Alleud, Wallonie, Belgique UCB Temps plein

    Make your mark for patients Nous recherchons un(e) Team Leader Downstream (FR) pour rejoindre notre département Biologics & Gene Therapy Clinical Manufacturing Sciences, basé sur notre campus de Braine-l'Alleud, Belgique. À propos du rôleVous jouerez un rôle clé en dirigeant une équipe de techniciens dans notre unité de production de thérapie...

  • Msat Lab Head

    il y a 3 semaines

    Braine-l'Alleud, Wallonie, Belgique UCB S.A. Temps plein

    Make your mark for patientsWe are looking for a MSAT Lab Head to join us in our Global Biologics Manufacturing Sciences & Technology (MSAT) team, based in Braine-l'Alleud, BelgiumAbout the roleThe MSAT Lab Head is responsible for:All lab activities and reports to the Head of Global Biologics MSAT. Timely delivering on all labbased MSAT activities by managing...

  • Procurement Lead Support

    il y a 1 mois

    Braine-l'Alleud, Wallonie, Belgique Randstad Temps plein

    We are looking for a Procurement Lead Support for one of our clients based in Braine-l'Alleud.Don't hesitate to contact me : - Life Sciences Wallonie.This is a contract as a Consultant (employee or freelance): project starts ASAP for 3/6 months. key responsibilitiesAs Temporary Procurement Support for Building and Facilities, you will play a critical role...