Innovative Drug Development Leader
il y a 3 jours
This is a scientific and strategic position in the DMPK department which is a part of Early Clinical Development - Translational Science (ECD-TS) group in the Patient Solutions Unit at UCB S.A.
The ideal candidate thrives in a collaborative work environment and is skilled at working on multiple projects concurrently along the full value chain from early discovery to post marketing.
The role holder will be responsible for ensuring a close relationship within the ECD-TS organization as well as other departments in Patient Solutions, utilizing expert in-depth knowledge of drug metabolism and transporter processes.
Key Responsibilities:
- Management responsibilities for employees in both Belgium and the UK
- Ensuring a highly innovative mindset among staff and guiding development of new assays in the DMPK/ADME arena
- Tactically assigning resources, implementing programs, and driving process improvement to meet financial expectations
- Quality and timely delivery of project deliverables in close contact with DMPK project representatives
- Representing UCB in conferences, acting as committee member on external scientific boards, and engaging in collaborations with academic institutions
- Interacting with and influencing key collaborators and stakeholders across Development Science for an overall understanding of the science needed to progress the UCB pipeline
- Contributing to clinical plans, regulatory communications, and submission documents
Requirements
To be successful in this role, you will need:
- A PhD in Pharmaceutics, Pharmacology, Drug Metabolism and Pharmacokinetics, or a related degree with significant industrial experience in DMPK science
- Demonstrated managerial and leadership skills
- Knowledge of the drug development process in a Pharma Industry environment
- Experience of leading, understanding, and hands-on drug metabolism and pharmacokinetics, both in vitro and in vivo studies, including human PK prediction, DDI prediction, and mechanistic understanding to support late-stage programs
- A strong understanding of studies using non-labeled and 14C and 3H-labeled compounds in animals and humans
- Proven skills for in-depth mechanistic understanding of DMPK-related issues and the impact and value of translation to humans
- Awareness of national/international regulatory principles and guidelines regarding assessment of ADME/DMPK properties of molecules
UCB S.A. is a global biopharmaceutical company focusing on neurology and immunology. We are inspired by patients and driven by science.
We have a caring, supportive culture where everyone feels included, respected, and has equitable opportunities to do their best work.
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