Postdoctoral Research Scientist – Flemish Cognitive Compass

ph3Postdoctoral Research Scientist – Flemish Cognitive Compass /h3 pThe VIB-KU Leuven Center for Neuroscience is part of the VIB Life Sciences Institute and embedded within the University of Leuven, one of the world's top 50 universities. Our mission is to accelerate breakthroughs in the understanding and treatment of neurodegenerative and neurological disorders. By combining deep mechanistic insight with translational ambition, we aim to develop next‑generation therapeutic strategies. /p pWe are now recruiting a postdoctoral researcher to join the Flemish Cognitive Compass — an ambitious, government‑funded initiative led by Prof. Dr. Bart De Strooper, a global authority in Alzheimer’s disease and other neurodegenerative disorders, affiliated with the University of Leuven–VIB. /p pThis multidisciplinary collaboration between VIB and the Universities of Leuven, Ghent, and Antwerp focuses on improving early detection of Alzheimer’s disease and identifying novel pathways and targets for disease‑modifying therapies. The research programme integrates advanced mechanistic studies with population health, disease genetics and biomarker discovery, all within a human‑centric framework. /p pbAbout the role /b /p pWe are seeking to recruit a postdoctoral researcher to establish an iPSC biobank for Alzheimer’s disease research and drive in vitro drug target and mechanistic discovery efforts using 3D triple culture systems within the Flemish Cognitive Compass programme. /p pbKey

responsibilities:
/b /p ul liCoordinate the derivation, quality control and biobanking of patient‑derived iPSC lines, in collaboration with clinical partners, core facilities and/or contract research organisations. /li liEstablish and oversee a 3D neuronal‑microglial‑astrocyte co‑culture platform, including workflow optimisation, automatisation, equipment procurement, and SOP development. /li liConduct mechanistic studies using the triple co‑culture platform, addressing both fundamental and translational questions in Alzheimer’s disease. /li /ul pbHow to apply /b /p pPlease complete the online application procedure and include a motivation letter describing previous research experience, along with a detailed CV. /p pbRequired documents: /b /p ul liDetailed CV /li liNames and contact details of 2 referees (if available) /li liFind out more about the De Strooper lab via this link /li liPhD degree (or equivalent) in Biomedical Sciences, Neuroscience, Molecular Biology, or related field. /li liStrong expertise in molecular or cellular neurobiology. /li liAbility to work both independently and collaboratively in a multidisciplinary setting. /li liExcellent organisational skills. /li liStrong attention to detail, data integrity and scientific rigour. /li liFluency in written and spoken English. /li liHands‑on experience with iPSC derivation, QC, maintenance and differentiation. /li liExperience with 3D and co‑culture in vitro models of the central nervous system. /li liExperience with cell‑based assays and plate‑based screening. /li liStrong track record of accurate data generation, documentation and experimental reporting. /li /ul /p