postdoc and PhD position to investigate SCAMP- aquaporin interplay in Arabidopsis
il y a 2 jours
Postdoctoral researcher and a PhD student to investigate the interplay between the Secretory Carrier Membrane Proteins and the plasma membrane aquaporins in Arabidopsis.
The VIB-UGent Center for Plant Systems Biology (PSB) is a world-leading plant science institute located at the heart of a renowned Plant Biotech campus in Ghent, Belgium. Its mission is to unravel plant biological processes and translate this knowledge into value for society. Please visit us at for more information.
Research at the Van Damme lab (https://www.vandammelab.be/) is centered around membrane trafficking in plants and we combine cell biological and biochemical/structural approaches to answer our research questions. We are highly passionate about the endocytic pathway that controls the plasma membrane proteome and we investigate its machinery, as well as its downstream cargo.
UCLouvain is the largest university in the French-speaking part of Belgium. It is located in Louvain-la-Neuve, 30 km south of Brussels. The Chaumont laboratory (https://uclouvain.be/en/research-institutes/libst/francois-chaumont.html) belongs to the Institute of Louvain Institute of Biomolecular Science and Technology (LIBST), which brings together more than 180 research staffs working in the field of biochemistry, molecular and cell biology. Chaumont's team is fascinated by the molecular and cellular mechanisms regulating physiological processes and, especially, by the regulation and function of aquaporins, which are involved in numerous developmental and physiological processes related to water relations but also to the movement of other physiological and signalling molecules.
The Van Damme lab and the Chaumont lab have joined forces via an FWO-weave project. Within this project, there are two 4-year positions available. A postdoctoral researcher position in the Van Damme lab and a PhD position in the Chaumont lab. The PhD student and the postdoc will work in close collaboration on the interplay between the secretory carrier membrane proteins (SCAMPs), which are cargo of the endocytic TPLATE complex (Arora et al., Plant Cell 2020 and Yperman et al. Science Advances 2021), and the plasma membrane aquaporins (PIPs). We aim to identify how the SCAMP proteins are involved in the trafficking and/or activity of the PIPs. The research will involve interactomics, live cell imaging, mutant analysis, structural modelling (e.g. AF2) as well as physiological assays on water permeability in Arabidopsis protoplasts as well as in Xenopus oocytes. The PhD student will be based in UCLouvain and the postdoc will be based in Ghent. As this is a truly joint project, both the student and the postdoc will be able to benefit from the available expertise in both labs.
Profile
Profile 1. PhD student
Master's degree in biology/bio-engineering, or equivalent, with a strong interest in plant biology and some experience in plant molecular and cellular biology or physiology.Profile 2. Postdoctoral researcher
Ph.D. degree in Biotechnology, Biochemistry, Biology, Bio-engineering, or equivalent. Required proven expertise in: live cell imaging, cloning (e.g. Golden Gate, Gibson), protein biochemistry, guidance of master and/or PhD students. Desired expertise in: interactomics, stomatal dynamics, Alphafold modelling. Experience in supervising Ph.D. students is also considered a plus.We welcome applications from dynamic individuals with a strong drive for science and motivation. Ideal candidates take initiative, possess a strong sense of responsibility, have critical thinking abilities, have excellent oral and written English communication skills, and have a collaborative mindset. Additionally, they should demonstrate the capacity to independently plan and execute research with precision.
We welcome the willingness of candidates to apply for personal fellowships in order to achieve their own individual funding. For the PhD student, this will imply applying for a FNRS and/or FRIA fellowship. Eligibility for Marie Curie and/or EMBO postdoctoral fellowship applications will be to your benefit.
Join us to undertake a highly innovative project that combines cell biology and plant physiology and that has the potential to discover novel ways how drought tolerance of plants can be increased.
We offer
State-of-the-art laboratory environment. An inclusive group atmosphere and a spot in a dynamic and diverse team of researchers. A versatile and challenging academic environment with very diverse contacts. Various opportunities to broaden your expertise and to train in many cutting-edge technologies. Training courses in academic, technical, and career skills. An initial 1-year contract, which can be extended up to 4 years.Starting Date: as soon as possible.
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