Emplois actuels liés à PhD molecular and computational neurogenomics - Antwerpen, Flandre - Universiteit Antwerpen
-
PhD position in Molecular and Computational Neurogenomics
il y a 3 semaines
Antwerpen, Flandre, Belgique TN Belgium Temps pleinPhD position in Molecular and Computational Neurogenomics, AntwerpClient:VIBLocation:Antwerp, BelgiumJob Category:OtherEU work permit required:YesJob Reference:0ba3d130b5cbJob Views:23Posted:23.01.2025Expiry Date:09.03.2025Job Description:We are a highly motivated international team of researchers at the Jordanova Lab and the Malysheva Lab at the VIB CMN. We...
-
PhD position in Molecular and Computational Neurogenomics
il y a 3 jours
Antwerpen, Flandre, Belgique VIB Temps pleinProject description We are a highly motivated international team of researchers at the (Jordanova Lab) and the (Malysheva Lab) at the VIB CMN. We are excited to announce a call for a joint PhD student in our labs to work on a challenging project at the interface of neurodegeneration, genomics, computational and systems biology. Charcot-Marie-Tooth...
-
Postdoctoral position in the lab of Computational Neurobiology
il y a 4 semaines
Antwerpen, Flandre, Belgique TN Belgium Temps pleinPostdoctoral position in the lab of Computational Neurobiology, AntwerpClient: VIBLocation: Antwerp, BelgiumJob Category: OtherEU work permit required: YesJob Reference: 399b5460269cJob Views: 5Posted: 03.03.2025Job Description:The Computational Neurobiology lab studies causal mechanisms underlying normal and aberrant cellular decision-making in the human...
-
Global PhD Partnerships
il y a 4 semaines
Antwerpen, Flandre, Belgique KU Leuven Temps pleinYou have the scientific curiosity that drives doctoral students with a keen interest in green technologies such as hydrogen. You are capable of operating independently, but also within multiple research teams composed of multidisciplinary backgrounds.The candidates:Hold a Master's degree in Mechanical Engineering or the equivalent.Have adequate English...
-
Administratieve duizendpoot – Onthaalmedewerker met hands-on-mentaliteit
il y a 4 semaines
Antwerpen, Flandre, Belgique VIB Temps pleinWij zijn op zoek naar een topper om ons administratief team te versterken Dankzij jou loopt alles op wieltjes. Ben jij enthousiast na het lezen van deze inleiding? Lees dan verderAbout The VIB-UAntwerp Center For Molecular Neurology, VIB-CMNOur Center currently hosts 7 PIs, each internationally recognized leader in the field of Neurogenetics or...
-
Antwerpen, Flandre, Belgique Universiteit Antwerpen Temps pleinLet's shape the future - University of Antwerp The is a dynamic, forward-thinking, European university. We offer an innovative academic education to more than students, conduct pioneering scientific research and play an important service-providing role in society. We are one of the largest, most international and most innovative employers in the region....
-
PhD Candidate in Architecture and Digitalisation
il y a 6 jours
Antwerpen, Flandre, Belgique TN Belgium Temps plein**About Us:**">We are the University of Antwerp, a leading European university with a strong focus on innovation, academic excellence, and societal impact. Our faculty of Design Sciences is looking for a highly motivated PhD candidate to join our research team as a Doctoral Scholarship Holder in the field of architecture, digitalisation, and real estate...
-
PhD Researcher in Urban Engineering
il y a 7 jours
Antwerpen, Flandre, Belgique TN Belgium Temps pleinJoin us at the University of Antwerp, where we strive to create a better future through innovative research and education.We are seeking a PhD researcher in urban engineering who can demonstrate excellent study results and skills in mixed research methods. You should have good communicative and entrepreneurial skills, as well as an independent attitude...
-
NLP PhD Researcher
il y a 4 semaines
Antwerpen, Flandre, Belgique TechWolf Temps pleinTechWolf is an AI company through and through – the AI team is responsible for defining and executing the overarching AI strategy. Handling topics like research, fairness, thought leadership and internal enablement, this small and high-impact team takes end-to-end ownership of AI initiatives within the company. The field of Natural Language Processing...
-
NLP PhD Researcher
il y a 3 semaines
Antwerpen, Flandre, Belgique Techwolf Temps pleinTechWolf is an AI company through and through – the AI team is responsible for defining and executing the overarching AI strategy. Handling topics like research, fairness, thought leadership and internal enablement, this small and high-impact team takes end-to-end ownership of AI initiatives within the company. The field of Natural Language Processing...
-
Antwerpen, Flandre, Belgique Universiteit Antwerpen Temps pleinLet's shape the future - University of Antwerp The is a dynamic, forward-thinking university in the second largest city in Belgium. We offer an innovative academic education to more than students, conduct pioneering scientific research and play an important service-providing role in society. We are one of the largest, most international and most...
-
PhD Position in Electromechanical Engineering
il y a 4 semaines
Antwerpen, Flandre, Belgique Polytechnicpositions Temps pleinPhD Position in Electromechanical EngineeringUniversity of AntwerpThe University of Antwerp is a dynamic, forward-thinking, European university. We offer an innovative academic education to more than 20,000 students, conduct pioneering scientific research, and play an important service-providing role in society. We are one of the region's largest, most...
-
Research Fellow Virus Ecology
il y a 3 jours
Antwerpen, Flandre, Belgique Instituut voor Tropische Geneeskunde Temps pleinMore than staff members at the Institute of Tropical Medicine (ITM) contribute every day to improving the health of millions of people worldwide. Our researchers conduct more than scientific projects in the fields of tropical medicine and international health. Our teaching staff welcomes more than professionals from around the world each academic year to...
-
Freelance Linguistics Expert
il y a 3 semaines
Antwerpen, Flandre, Belgique Mindrift Temps pleinFreelance Linguistics Expert - AI TutorAt Mindrift, innovation meets opportunity. We believe in using the power of collective intelligence to ethically shape the future of AI.Our goal? Advance the field of artificial intelligence through collaborative Generative AI projects with domain experts. The Mindrift platform allows experts to dive into a variety of...
-
Process Architect and Materials Scientist
il y a 7 jours
Antwerpen, Flandre, Belgique Qplox engineering Temps pleinOur Team">We are a multidisciplinary team dedicated to pushing the boundaries of Silicon Photonics research and development.">Research Focus">Our team focuses on developing new material systems and devices for existing Silicon Photonics process platforms, incorporating specialized materials such as Lithium Niobate (LiNbO3), Barium Titanate (BaTiO3), organic...
-
Silicon Photonics Process Architect and Expert
il y a 2 jours
Antwerpen, Flandre, Belgique Qplox engineering Temps pleinJob Overview: Qplox engineering is seeking a highly skilled R&D Process Architect to lead the integration of active components into our Silicon Photonics platforms. The successful candidate will play a key role in defining new process architectures, developing fabrication processes, and ensuring seamless integration of new active photonic devices into our...
-
Digital and Analog IC Engineer
il y a 15 heures
Antwerpen, Flandre, Belgique Vivid Resourcing Temps pleinJoin us at Vivid Resourcing as a Digital and Analog IC Engineer and contribute to the development of innovative telecommunications solutions.Job Summary:Design and develop high-performance digital circuit designs for next-generation telecommunications applications.Collaborate with system architects, verification engineers, physical design teams, and process...
-
Antwerpen, Flandre, Belgique EnergyVille Temps pleinBeschrijvingThe Department of Electrical Engineering (ESAT) at KU Leuven offers a postdoc position in the field of Modelling of power electronic converter-based systems for harmonic and small-signal stability analysis.Within the Electrical Energy & Computer Architectures (Electa) division and EnergyVille, the research team led by prof. Jef Beerten focuses on...
-
Digital Real Estate Expert
il y a 6 jours
Antwerpen, Flandre, Belgique TN Belgium Temps plein**Our Team:**">We are a team of dedicated researchers and professionals at the University of Antwerp, committed to advancing knowledge and innovation in the field of architecture, digitalisation, and real estate markets.**The Role:**We are seeking a highly motivated PhD candidate to join our team as a Doctoral Scholarship Holder. In this role, you will work...
-
High-Speed Analog and Mixed-Signal Circuit Designer
il y a 19 heures
Antwerpen, Flandre, Belgique Vivid Resourcing Temps pleinVivid Resourcing is seeking an experienced Telecommunications ASIC Design Expert to join our innovative team. As a key member of our design team, you will be responsible for developing cutting-edge telecommunications solutions.About the Role:Design and develop high-performance digital circuit designs for next-generation telecommunications...
PhD molecular and computational neurogenomics
il y a 1 semaine
Let's shape the future - University of Antwerp
The is a dynamic, forward-thinking, European university. We offer an innovative academic education to more than students, conduct pioneering scientific research and play an important service-providing role in society. We are one of the largest, most international and most innovative employers in the region. With more than employees from different countries, we are helping to build tomorrow's world every day. Through top scientific research, we push back boundaries and set a course for the future – a future that you can help to shape.
The Faculty of Pharmaceutical, Biomedical and Veterinary Sciences is looking for a full-time (%) PhD in the field of Molecular and Computational Neurogenomics
Position
We are a highly motivated international team of researchers at the (Jordanova Lab) and the (Malysheva Lab) at the VIB CMN. We are excited to announce a call for a joint PhD student in our labs to work on a challenging project at the interface of neurodegeneration, genomics, computational and systems biology.
The overarching goal of this proposal is to understand why and how dysregulation of omnipresent and constantly expressed ARS proteins leads to dying-back neurodegeneration and affects specifically the peripheral neurons (PNs). This neuronal population contains the most polarized cells in our body and their sophisticated morphology and function render them highly susceptible to degeneration. The preliminary data generated in-house as well as the available public data suggest mechanisms involving genetic, epigenetic and chromatin organisation factors governing the cell-type specific response to ARS mutations. Therefore, an integrative genome-wide cis-regulatory network analysis approaches, developed and employed in the Malysheva Lab, are required to reveal these mechanisms.
With the proposed project we aim to bridge this gap in our knowledge of cis-regulatory mechanisms underlying this disease and reveal the mechanisms underlying the strong cell-type specific effect of the CMT-causing YARS mutations. For this we will generate high-resolution spatial chromatin organisation, chromatin accessibility and gene expression data for all major cell types forming the peripheral nerve environment (as well as controls), generated from the patient-derived iPSCs and integrate these data into the cis-regulatory networks. Following cis-GRN network reconstruction and formal graph analysis, we will identified key regulatory factors governing cell-type specific reponse to CMT-causing mutations. Finally, we will validate the identified key (epi)genetic molecular and eplore their therapeutic potential in in vitro and in vivo disease models.
Profile
You have an MSc in Systems Biology, Molecular Biology, Natural Sciences or related disciplines You are motivated and enthusiastic to learn and expand both computational and experimental skill set You have an analytical mindset You are able to summarize data extracted from the literature and clearly shape research objectives You are able to efficiently communicate with experimental and computational scientists You have excellent communication and writing skills in EnglishRequired skills
confident in basic molecular biology techniques, such as cell cultures, basic genomics data generation knowledge of (theory behind) gene regulatory mechanisms and multimodal data integration basic/intermediate programming skills in R and/or python Ability to adapt to the research environments while being full members of two labsDesirable skills
statistical analysis basic processing of NGS data experience with iPSC and/or cell culturing knowledge of and some experience with genetic perturbation assays, such as CRISPRWhat we offer
As part of the and , the applicant will benefit from established collaborations and access to centralized facilities with expertise in genomics, functional genomics and cell biology, proteomics, cutting-edge microscopy, structural biology, technology development, and bioinformatics.
VIB provides a highly interactive environment and ample training opportunities for its researchers. In addition, the VIB-UAntwerp Center for Molecular Neurology is located in the city of Antwerp, the capital of Flanders, offering a culturally and historically rich, and ethnically diverse environment.
The VIB-UAntwerp Center for Molecular Neurology has 7 PIs and hosts internationally recognized leaders in the field of Neurogenetics and Neuroinflammation. Current research groups address a broad set of questions related to neurodegenerative diseases of the central and peripheral nervous system, with an emphasis on understanding the genetic etiology and developing diagnostics and treatment methods for these diseases. Approaches range from human genetics, genomics, protein biochemistry and neuronal and glial cell biology to integrative systems and computational biology. Models include yeast, fly, mouse, and pluripotent human cell systems. Research groups have access to state-of-the-art research and top-notch support core facilities and attract talented international scientist from across the world.
By the end of the PhD the successful candidate will graduate with a highly competitive set of experimental and computational skills, such as generation and characterization of patient-derived cell-type specific samples, state-of-the-art molecular biology techniques, multimodal data generation and integration, gene regulatory network reconstruction and wide range of machine learning approaches The host labs will provide financial support for the whole length of the PhD. Access to state-of-the-art infrastructure and core facilities in a vibrant, world-class research environment operating at an international level Dedicated training programs available through VIB and UAntwerp to broaden your expertise and enhance your skillset A stimulating and international research environment A strong and dynamic network of international collaborators The planned start date is as soon as possible. Your monthly scholarship amount is calculated according to the for doctoral scholarship holders on the pay scales for Contract Research Staff (Dutch: Bijzonder Academisch Personeel, BAP). You will receive ecocheques, Internet-connectivity allowance, and a bicycle allowance or a full reimbursement of public transport costs for commuting. You will do most of your work at Campus Drie Eiken in a dynamic and stimulating working environment. Find out more about working at the University of Antwerp . The selection committee reviews all applications as soon as possible after the application deadline. As soon as a decision is made, we will notify you. If you are still eligible after the pre-selection, you will be informed about the possible next step(s) in the selection procedure.