Process Development Chemist

il y a 2 semaines


Luik stad, Belgique Trasis Temps plein

As a Process Development Chemist, you are responsible for carrying out API synthesis development projects in line with the company's strategy. You take part in drawing up the specifications for the products to be developed, design and carry out the experimental plans required for this purpose, and ensure that the results comply with the specifications for each product. When development is finalized, you provide the data and support needed by the industrialization team to get the product into production.**Responsibilities**
- You are in charge of designing the processes required for API synthesis, based on an in-depth bibliographical study.
- You write the specifications for each product.
- You consult and master the technical characteristics of production equipment and consumables, and define processes compatible with them.
- You understand HSE and regulatory requirements and take them into account in development.
- You master customer requirements and take them into account in development.
- You participate in risk analyses (products, processes, cleaning).
- You define research protocols, set up the experimental plans required for product development, robustness assessment and continuous improvement.
- You are proficient in analytical development (HPLC, NMR, IR) for quality control of products and intermediates.
- You are familiar with conventional organic purification techniques (recrystallization, flash chromatography, purification on silica, selective precipitation).
- You write product development reports.
- You communicate pro-actively and regularly with your n+1 and with the Project Manager.
- You work in compliance with safety and laboratory regulations.
- You participate in the drafting of patents.
- You define and justify specifications for APIs and synthesized intermediates.
- You write scientific publications and take part in conferences.
- You participate in the development and management of subsidized research projects.
- You carry out customer installations when required.
- Participate in the search for and selection of suppliers.
- Participate in regulatory inspections (FAMHP, etc.) and others as required.

Profile
- You have a Master’s or PhD degree in organic synthesis chemistry.
- You ideally have initial experience and knowledge of the radiopharmaceutical industry.
- You are an expert in organic and peptide synthesis.
- You are an expert in peptide purification techniques.
- Knowledge of continuous flow synthesis is an asset.
- You are fluent in French and English.
- Excellent writing skills (French and English).
- You are familiar with the Office Suite.
- You are able to take the initiative.
- You are innovative, pragmatic and organized, with a sense of priorities.
- You have a scientific mind: precision, rigor, synthesis and analysis.
- You enjoy working as part of a team.

Do you want to become a major player in the global fight against cancer?

At Trasis, we give you the opportunity to work with cutting-edge technologies and to contribute to the improvement of cancer diagnosis and therapy techniques. Through your actions, you will have the opportunity to have a positive impact on the services provided to users and patients.

The opportunity to participate in building and improving processes in a growing company.

We offer a young and friendly work atmosphere, a flexible and dynamic environment.
- An attractive and flexible salary according to your experience and performance, with extra-legal benefits.


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