Phd in Molecular Microbiology: Unraveling Mutational Robustness and Evolvability in Bacteria
il y a 1 jour
**Research topic**:
Whereas mutations are the driving force for adaptive evolution, many genetic alterations exert negative fitness effects. The effect of some mutations can be buffered by the activity of specific genes encoded elsewhere in the genome. These so-called buffering genes give rise to mutational robustness which implies that a phenotype remains invariant in spite of mutations to its genotype, thereby diminishing the organism’s capacity to adapt to new environments. At present, mutational robustness and evolvability remain poorly understood.
- Pathways involved in robustness against _de novo_ mutations
- Type of genetic variation that can be buffered Molecular mechanisms underlying mutational robustness
**Skills**:
**Essential**
**Desirable but not required**
- Computational background is a plus
**Key personal characteristics**
- Motivated & enthused team player who enjoys working in a fun, diverse multicultural team
**We offer**:
- A full-time PhD position for one year; after a positive evaluation, the contract can be extended to three additional years (four years in total)
- A working climate where trust, (international) collaboration, and commitment are essential
- An excellent young, stimulating and supportive international research environment
- High level scientific training at a top-ranked university; training in academic, thematic and soft skills. Access to state-of-the art tools and infrastructure
**How to apply?**:
Applications should be submitted through this portal by July 7th 2025 and should contain:
- Full CV including previous research experience and publication list (if applicable)
- Concise cover letter describing your motivation and career goals
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