Senior Technical Assistant

ppToday, precision medicine coupled with advanced diagnostics is taking over. However, those innovations in medicine come with an ever-increasing price tag driven by more expensive and complicated solutions making them less accessible unless we do something about it. /ppbSignatur Biosciences /b was established with the mission of making cutting-edge diagnostic tools accessible to more patients around the world. As a startup we have developed a technology to profile complex molecular signatures in a single reaction using qPCR machines already in place in every biomedical lab around the world. Signatur Biosciences is a startup with a remote workforce, predominantly in London, UK, and is establishing a new laboratory facility in Liège, Belgium. /ppWe're worried about accessibility in precision diagnostics and are building a team of individuals who share our passion for solving this problem through close collaboration and a sense of urgency. We're building a different kind of company, where employees think like owners, act with authority, and collaborate closely with one another. /ppWe are seeking a highly motivated and driven Senior Technical Assistant to join our team to help establish our new Belgium laboratory facility (full time, on site). In this role, under the direction of the Head of Laboratory Operations, you will be responsible for developing, implementing and maintaining all necessary procedures and process required for a state-of-the-art ISO13485 compliant laboratory facility and for the generation of data to support the development of next generation molecular diagnostic products. You will join Signatur Biosciences at an exciting time as we are a small start-up company looking to grow. You will be part of an expanding laboratory operations team but also interact with colleagues across the company who have the shared mission to make precision diagnostics more accessible. If you are a highly motivated and driven self-starter with a passion for novel diagnostics development, we'd love to speak with you /ppbAbout the role: /bAs a Senior Technical Assistant, you will be responsible for ensuring the efficient and effective operations of the laboratory by performing regular maintenance, laboratory housekeeping activities and coordinating the activities of team members. You will also be responsible for the execution and recording of laboratory experiments in accordance with specified work instructions and protocols. /ppbTechnical Expertise /b /ppExpert in PCR /ppExperience with nucleic acid extraction /ppExperience with maintenance and calibration of laboratory equipment /ppExperience of timely and accurate laboratory record keeping /ppExperience in coordinating laboratory activities /ppbSkills, Experience Attributes /b /ppBachelor of Science degree in biology, molecular biology, synthetic biology, bioengineering, or similar /ppAt least 3 years of hands-on molecular biology laboratory experience (not including course work) /ppPrevious start-up or diagnostic industry experience /ppExperience in using automated PCR set-up instruments /ppKnowledge in the field of molecular diagnostics /ppFamiliarity with a scientific programming language (Python, R, Matlab or Julia) /ppExperience of working within biobanking requirements /ppExperience in laboratory supervision of staff /ppExperience working within a Quality Management System for In Vitro Diagnostic development (ISO13485) /ppbMain

Responsibilities:
/b /ppPeople and Functional Development /ppAssist the Head of Laboratory Operations with the planning, supervision and coordination of laboratory activities. /ppResponsible for ensuring a safe and effective laboratory environment through completion of daily maintenance and housekeeping activities /ppMaintain and calibrate laboratory equipment /ppOrder receive laboratory supplies, equipment and apparatus /ppAssist in the storage, handling and maintenance of records with regards biological samples in accordance with the relevant requirements /ppBe responsible for work instructions, training and maintenance of specific laboratory processes/equipment as a lab process expert /ppContribute to the laboratory processes / procedures implementation in accordance with In Vitro Diagnostic development (ISO13485) /ppSupport the Head of Laboratory Operations in the implementation and monitoring of metrics (Key Performance Indicators) of laboratory efficiency effectiveness /ppContribute towards the continuous improvement of the laboratory facility and operations of Signatur Biosciences /ppTraining and coaching of team members /ppProject and Product Delivery /ppConduct laboratory studies in accordance with work instructions and/or study protocols in support of research and/or product development projects including: /ppPerforming qPCR experiments manually or using high-throughput liquid handlers (for example i.
DOT machine) /ppCarry out nucleic acid extractions according to specified protocols or work instructions /ppExecute lab