Principal Scientist Medicinal Chemistry

il y a 23 heures


Antwerpen, Flandre, Belgique TN Belgium Temps plein

Social network you want to login/join with:

Principal Scientist Medicinal Chemistry, AntwerpClient:

Galapagos

Location:

Antwerp, Belgium

Job Category:

Other

EU work permit required:

Yes

Job Reference:

f8379ff4c168

Job Views:

3

Posted:

06.03.2025

Expiry Date:

20.04.2025

Job Description:

Pleased to meet you, we are Galapagos, a dynamic fast-growing Biotech company. We're in the business of changing lives.

Galapagos' mission is to make a lasting positive contribution to society through the discovery of innovative therapies for diseases with large unmet medical need. Galapagos' historic focus on developing first-in-class medicines based on the discovery of novel targets in inflammation and fibrosis has led to the successful launch of our first medicine in rheumatoid arthritis in 2020 and in ulcerative colitis in 2021.

Galapagos is now entering an exciting new chapter to expand and diversify its pipeline for the future, starting with oncology, specifically CAR-T cell therapy, a transformative treatment of different types of cancer. Through the combined acquisitions of CellPoint and AboundBio, we are propelling ourselves into next-generation cell therapies.

We are looking for a Principal Scientist Medicinal Chemistry - Mechelen, BE.

Scope of the Job

We are seeking a highly accomplished and creative Principal Scientist in Medicinal Chemistry to contribute to our drug discovery efforts and development of novel medicines. The successful candidate will be a key scientific contributor and leader, overseeing projects and teams to drive scientific excellence and innovation, reporting to the Senior Director of Medicinal Chemistry.

Your Role
  1. Lead Medicinal Chemistry Projects: Take ownership of medicinal chemistry projects, employing expert knowledge to optimize physicochemical properties, develop structure-activity relationships, and drive the design of novel molecules, ultimately leading to the identification of clinical candidates. Formulate hypotheses, design and synthesize novel compounds to engage disease-modifying targets, and contribute decisively to drug discovery programs from hit ID to lead generation and optimization and clinical candidate nomination.
  2. Cross-Functional Collaboration: Work collaboratively in a cross-functional matrix leadership role, building strong relationships with peers within project teams to support the advancement of compounds towards clinical candidate selection. Collaborate across disciplines with biologists, structural biologists, computational chemists, pharmacologists, and other experts to leverage state-of-the-art techniques.
  3. Team Leadership and Mentorship: Provide scientific leadership to medicinal chemistry team members, mentoring and coaching on SAR analysis, compound design, and synthetic route optimization. Lead and develop colleagues to promote personal growth and create new scientific capabilities. Promote a culture of safety and adhere to EH&S guidelines.
  4. Project Management: Plan, execute, interpret, and optimize structure-activity relationship campaigns, with a focus on the design of high-impact small molecules. Manage project-specific resources, both internal and external, and support the preparation of project-specific documents for patent filing.
  5. Communication and Presentation: Present and actively participate in project and departmental research meetings. Author technical documents, patent applications, and scientific manuscripts, as well as prepare and present at scientific conferences.
#J-18808-Ljbffr

  • Antwerpen, Flandre, Belgique BOSS Energy Consulting Temps plein

    About BOSS Energy Consulting LtdWe are a leading Clean Technology company seeking to hire a Senior Researcher to join our industrialization team.The successful candidate will assist on the development of catalytic chemistry research from the R&D phase into plant manufacturing specifications.Key Responsibilities: Assist the advancement of innovative...


  • Antwerpen, Flandre, Belgique TN Belgium Temps plein

    Principal Regulatory Consultant, AntwerpClient:Quality managementLocation:Antwerp, BelgiumJob Category:OtherEU work permit required:YesJob Reference:2c41a93966f5Job Views:25Posted:23.01.2025Expiry Date:09.03.2025Job Description:The UK team of the international QbD group, is a specialist regulatory and pharmacovigilance consultancy company. Our services...


  • Antwerpen, Flandre, Belgique Fairbrics Temps plein

    **About Fairbrics**We are a pioneering company that is revolutionizing the approach to sustainability. Our innovative approach involves transforming carbon dioxide from industrial emissions into valuable chemicals used in polyester production—the primary material for clothing.We are seeking an experienced and skilled individual to join our team as a Junior...

  • QC analist/scientist

    il y a 2 semaines


    Antwerpen, Flandre, Belgique MindCapture Temps plein

    B. is readily available and an allrounder in the lab. He has experience with analytical chemistry and within the R&D industry. In addition, he is someone who likes to roll up his sleeves and is flexible and communicative. Someone who can work autonomously, but also works smoothly in a team.B. is a chemist with expertise in organic and reaction chemistry who...


  • Antwerpen, Flandre, Belgique TN Belgium Temps plein

    Social network you want to login/join with:R&D Material Scientist for Batteries, AntwerpClient:VITOLocation:Antwerp, BelgiumJob Category:OtherEU work permit required:YesJob Reference:1e7aa3817c29Job Views:2Posted:06.03.2025Expiry Date:20.04.2025Job Description:Eager to contribute to innovative solutions for a sustainable future? Come join us at VITO – an...

  • Clinical Trials Scientist

    il y a 15 heures


    Antwerpen, Flandre, Belgique Institute of Tropical Medicine Temps plein

    Department of Clinical Sciences - Clinical Trials Unit More than 500 staff members at the Institute of Tropical Medicine (ITM) contribute every day to improving the health of millions of people worldwide. Our researchers conduct more than 100 scientific projects in the fields of tropical medicine and international health. Our teaching staff welcomes more...

  • Clinical Trials Scientist

    il y a 15 heures


    Antwerpen, Flandre, Belgique Institute of Tropical Medicine Temps plein

    Department of Clinical Sciences - Clinical Trials Unit More than 500 staff members at the Institute of Tropical Medicine (ITM) contribute every day to improving the health of millions of people worldwide. Our researchers conduct more than 100 scientific projects in the fields of tropical medicine and international health. Our teaching staff welcomes more...

  • Clinical Trials Scientist

    il y a 11 heures


    Antwerpen, Flandre, Belgique Institute of Tropical Medicine Temps plein

    Department of Clinical Sciences - Clinical Trials Unit More than 500 staff members at the Institute of Tropical Medicine (ITM) contribute every day to improving the health of millions of people worldwide. Our researchers conduct more than 100 scientific projects in the fields of tropical medicine and international health. Our teaching staff welcomes more...


  • Antwerpen, Flandre, Belgique TN Belgium Temps plein

    Social network you want to login/join with:Client:OrdinaLocation:Antwerp, BelgiumJob Category:OtherEU work permit required:YesJob Reference:6df9ac043b21Job Views:27Posted:03.03.2025Expiry Date:17.04.2025Job Description:Your ImpactAs an experienced Computerized System Validation (CSV) Engineer, you play a key role in the implementation and management of...


  • Antwerpen, Flandre, Belgique TN Belgium Temps plein

    As a Manufacturing Execution System (MES) Engineer, you will be jointly responsible for increasing efficiency and reducing risks within production processes. Your knowledge of MES PAS-X, Delta V, Siemens or another known system, combined with your general process knowledge within Life Sciences, will help you to estimate and implement optimizations in...


  • Antwerpen, Flandre, Belgique TN Belgium Temps plein

    Sibelco is a global material solutions company. We mine, process and sell industrial minerals at locations worldwide, focused primarily on silica, clays, feldspathics, and olivine. We are also leaders in glass recycling. The Sibelco Group operates over 110 production sites in 31 countries, with a team of over 5,000 people.Job Title: Lab Technician GlassJob...


  • Antwerpen, Flandre, Belgique Karlstad University Temps plein

    Postdoctoral researcher in chemical biology and drug discovery in the area of protease researchLet's shape the future – University of AntwerpThe University of Antwerp is a dynamic, forward-thinking, European university. We offer an innovative academic education to more than 20000 students, conduct pioneering scientific research and play an important...


  • Antwerpen, Flandre, Belgique Institute of Tropical Medicine Temps plein

    **A Career Opportunity**The Institute of Tropical Medicine is offering a challenging opportunity for an experienced Clinical Trials Scientist to join our dynamic team at the Clinical Trials Unit (CTU). Our mission-driven team is focused on addressing health problems in Belgium and overseas in resource-limited settings, conducting over 100 scientific projects...

  • Clinical Trials Researcher

    il y a 9 heures


    Antwerpen, Flandre, Belgique Institute of Tropical Medicine Temps plein

    **Overview of the Institute of Tropical Medicine**The Institute of Tropical Medicine is a renowned international institute dedicated to improving global healthcare through scientific research. As a leading authority in tropical medicine and international health, our researchers conduct over 100 scientific projects in various fields, welcoming more than 500...


  • Antwerpen, Flandre, Belgique TN Belgium Temps plein

    Social network you want to login/join with:For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance,...


  • Antwerpen, Flandre, Belgique Polytechnicpositions Temps plein

    Postdoctoral Position in Chemical EngineeringUniversity of AntwerpThe University of Antwerp is a dynamic, forward-thinking, European university. We offer an innovative academic education to more than 20,000 students, conduct pioneering scientific research and play an important service-providing role in society. We are one of the largest, most international...


  • Antwerpen, Flandre, Belgique Karlstad University Temps plein

    Post-doctoral candidates Microfluidics for sustainable photo(electro)catalysis and sensingLet's shape the future - University of AntwerpThe University of Antwerp is a dynamic, forward-thinking, European university. We offer an innovative academic education to more than 20,000 students, conduct pioneering scientific research and play an important...

  • Senior Scientist

    il y a 3 semaines


    Antwerpen, Belgique Johnson & Johnson Temps plein

    Johnson & Johnson is hiring a Senior Scientist, Discovery Chemistry to join our team in Beerse, Belgium. Key Responsibilities: - Further design, develop and optimize a highly efficient purification workflow for analysis and purification of compounds from medicinal chemistry projects particularly in peptide synthesis singletons and libraries utilizing...


  • Antwerpen, Belgique Johnson & Johnson Temps plein

    **Based on your professional experience and educational background, we have the flexibility to tailor the position's level and responsibilities accordingly.** Janssen Research & Development seeks to bring creative and effective treatments in oncology, neuroscience, infectious diseases, cardiovascular diseases and metabolism, immunology, and pulmonary...


  • Antwerpen, Belgique Universiteit Antwerpen Temps plein

    Niet gevonden wat je zocht? Sla je zoekopdracht dan op en maak een job alert aan op de online sollicitatiemodule om automatisch op de hoogte te blijven van interessante toekomstige vacatures. Meer informatie kan je hier vinden. Departement: Faculteit Farmaceutische, Biomedische en Diergeneeskundige Wetenschappen Regime Voltijds **Let’s shape the future -...


  • Antwerpen, Belgique Universiteit Antwerpen Temps plein

    Niet gevonden wat je zocht? Sla je zoekopdracht dan op en maak een job alert aan op de online sollicitatiemodule om automatisch op de hoogte te blijven van interessante toekomstige vacatures. Meer informatie kan je hier vinden. Departement: Faculteit Farmaceutische, Biomedische en Diergeneeskundige Wetenschappen Regime Voltijds **Let’s shape the future -...

  • Data Scientist @ Basf

    il y a 1 jour


    Antwerpen, Belgique Amon Consultants Temps plein

    **Bedrijf**: BASF is het grootste chemiebedrijf ter wereld. Het is een Duits bedrijf met zijn hoofdvestiging in Ludwigshafen am Rein, meer dan 380 productievestigingen en een jaaromzet van 78,6 miljard euro. De afkorting BASF staat voor Badische Anilin - & Soda-Fabrik (Nederlands: Badense Aniline - & Soda-Fabriek). De firma is in 1865 opgericht door...


  • Antwerpen, Belgique Johnson & Johnson Temps plein

    **About Johnson & Johnson**: Pharmaceutical & Material Sciences is, within the Pharmaceutical Development & Supply (PPDS) organization of the Pharmaceutical Companies of Johnson and Johnson, responsible for preformulation & biopharmaceutics, solid state form selection, material selection and qualification. In Belgium (Beerse) there is a vacancy for a...


  • Antwerpen, Belgique AAK International Temps plein

    **Laboratory Supervisor, Bakery Applications** Our story goes back more than 150 years, to the chilly southern coast of Scandinavia. From our early success in Sweden and Denmark, we’ve grown into the world’s leading specialist producer of plant-based oils, employing more than 4,000 people all across the globe. We work with our customers to make the...

  • Qc New Product Introduction

    il y a 4 semaines


    Antwerpen, Belgique Johnson & Johnson Temps plein

    **QC New Product Introduction (NPI) Analytical Integrator (M/F/X)** For more than 130 years, diversity, equity & inclusion (DEI) have been part of our cultural fabric at Johnson & Johnson and woven into how we do business every day. Our commitment to respect the dignity and diversity of all is embedded in our Credo. We know that the success of our business...


  • Antwerpen, Belgique Universiteit Antwerpen Temps plein

    Niet gevonden wat je zocht? Sla je zoekopdracht dan op en maak een job alert aan op de online sollicitatiemodule om automatisch op de hoogte te blijven van interessante toekomstige vacatures. Meer informatie kan je hier vinden. Departement: Departement Bio-ingenieurswetenschappen Regime Voltijds **Let’s shape the future - University of Antwerp** The...


  • Antwerpen, Belgique Universiteit Antwerpen Temps plein

    Niet gevonden wat je zocht? Sla je zoekopdracht dan op en maak een job alert aan op de online sollicitatiemodule om automatisch op de hoogte te blijven van interessante toekomstige vacatures. Meer informatie kan je hier vinden. Departement: Faculteit Sociale Wetenschappen Regime Voltijds **Let’s shape the future - University of Antwerp** The University...