Analytical Scientist
il y a 3 semaines
Analytical Scientist
To strengthen our Analytical Sciences for our client, we are looking for an Analytical Scientist with strong experience in analytical development, process support, and at least hyphenated analytical techniques (Nuclear Magnetic Resonance – NMR). The position is based in our Characterization and Material Sciences department on their site in Braine l'Alleud, Belgium.
In this role, you will contribute to the end-to-end analytical development of our small molecule and peptide portfolio, from preclinical through to the launch and the lifecycle of our marketed products.
The Responsibilities
- Ensuring day-to-day NMR analysis.
- Ensuring release and stability testing of API, standards, and clinical batches from Phase I to Phase III.
- Ensuring release testing of raw materials, starting materials, degradation products, and intermediate of synthesis.
- Developing and validating fit-for-purpose analytical methods according to aQbD principles (risk assessment, DoE, modelling) for APIs, Drug Products, and In Process Control (IPC).
- Transferring analytical methods to CDMOs, QC, and manufacturing units and participating in their lifecycle management.
- Providing high-quality documentation of all technical work performed in the laboratory.
- Actively participating in project meetings as well as internal scientific meetings.
- Participating in the implementation of new state-of-the-art analytical methodologies and process improvements including bibliographic survey, technical scouting, and innovative methodological evaluation.
Education Experience and Skills Required
- This position requires a bachelor/master's degree with at least 2 years' experience (e.g., Analytical Chemistry) in the pharmaceutical industry.
- Competence and autonomy in analytical development with NMR spectrometers.
- Basic knowledge of NMR is highly recommended.
- Key areas of expertise are the following:
- Experience in NMR for characterization, quantification, and structural identification of compounds.
- Experience in the development of analytical methods for small molecules and/or peptides.
- Understanding of regulatory, GMP, and safety environments.
- Experience using Bruker instruments and knowledge of Topspin/MestReNova is a plus.
- Knowledge of organic chemistry to facilitate the interpretation of spectroscopy results is a plus.
- Knowledge of other characterization techniques (MS / IR / NIR / …).
- Key skills are the following:
- Able to work and respect the procedures in a regulated environment including good practices and HSE.
- Good interpersonal, verbal, and written communication skills in French and/or English.
- Team player, highly motivated with a strong client orientation.
- Demonstrated motivation for laboratory work and hands-on experience with analytical instruments.
- Ability to work in a matrix organization in different technical areas.
- Be able to find autonomously technical solutions and activate all appropriate internal/external experts to solve the issue.
- Be able to efficiently translate the data collected into knowledge that meets the needs of the project.
- Must be able to manage scientific tasks independently to meet deadlines within given challenging timelines.
Our Offer
Jefferson Wells offers you a permanent contract as a consultant with an attractive salary package and access to training in both technical and non-technical skills. We'll be your career partner every step of the way.
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