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Associate Scientist, Molecular Analytics Platform
Il y a 2 mois
Site Name:
Belgium-Rixensart
Posted Date:
Feb 5 2024
Job purpose:
Your responsibilities:
- Work on the bench in the labs (> 60%)
- Contribute to the development and deployment of new nucleic acid sequencing protocols for the sequencing of plasmid DNA, genomic DNA, direct sequencing of mRNA based on Illumina and Oxford Nanopore technologies
- Ensure the development of analytical methods for purity, identity and sterility
- Contribute to the development, qualification, validation and transfer of innovative genetic characterization assays/technologies based on stateoftheart NAT
- Develop detailed experimentation protocols and executes the planning/organization of the experiments in his/her scope of activities
- Execute analytical methods for the characterization of mRNA and plasmid DNA
- Execute analytical methods for the genetic characterization of genetically engineered microorganisms, including recombinant plasmids
- Execute analytical methods for the release of Phase I, II and III clinical lots
- Analysis and interpretation of the data, including reporting and presentation
- Write scientific reports
- Interact with Belgium
- Interact and act in a complex matrix with several stakeholders from different departments (Research, Development, QC, RA, QA)
- Interact with other GSK Vaccines Research and Development Centers (US and IT) and external partners
- Ensure implementation of QbD (Quality by design) in the development of assays
- Agile principles driven
- Good writing skills and fluent in French and English
- Contribute to the various activities of the group, including laboratory organization and compliance and analytical instruments installation, validation and maintenance
- Ensure that SOP are applied and respected
- Ensure that security rules are followed
- Comply with your training matrix
Why you?_**
Basic Qualifications:
- We are looking for professionals with these required skills to achieve our goals:_
- Master degree (biotechnology, molecular biology, biochemistry, (molecular) bacteriology, (molecular) microbiology,...) with 2 to 5 years of experience in the industry (in biologics / biopharmaceuticals / pharmaceutics) or equivalent by experience
- Specific knowledge (mandatory): deep knowledge and routine use of at least one of the stateoftheart Next Generation Sequencing technologies (Oxford Nanopore Technologies preferred)
- Deep knowledge of bioinformatics is a plus
- Experience in a lab environment focusing on analytics of biomolecules
- Languages: French and/or English
- Good organizational skills
- Team work
- Ability to conduct literature and online research, continuous search of new methods
- Identification of critical method parameters and plan to evaluate them
- Specific knowledge: knowledge of at least one of the stateoftheart NGS technology (ONT preferred)
- Junior between 2 and 5 years of experience
Preferred qualifications:
- If _you _have the following characteristics it would be a plus:_
- Good writing and presentation skills
- Good communicator
- Attention for details, eager to learn and driven by curiosity
- Bacteriology, microbiology techniques, including plasmid biology
- Nucleic acid extraction and electrophoresis
- PCR, QPCR and ddPCR
- Molecular Biology techniques (including sequencing, Southern blot, restrictions, reverse transcription, in vitro transcription, electrophoresis, etc.)
- GMP basics is a plus
If you have a disability and require assistance during the course of the selection process, you will have the opportunity to let us know what specific assistance you require in order to make suitable arrangements.
Why Us?
GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organization where people can thrive.
Getting ahead means preventing disease as well as treating it, and we aim to positively impact the health of 2.5 billion people by the end of 2030.
Our success absolutely depends on our people.While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive.
We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy.
We're committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.
**Important notice to Employment businesses/ Agencies