Gene Therapy Upstream Process Scientist

il y a 1 semaine


Brainel'Alleud, Wallonie, Belgique UCB S.A. Temps plein

Make your mark for patients


We are looking for a
Gene Therapy Upstream Process Scientist who is
easy going to join us in our
Gene Therapy CMC Process Development team, based in
Belgium.


About the role


The Gene Therapy (GT) Upstream Process Scientist will be responsible for
supporting Upstream Process Development activities for UCB's recombinant adeno-associated virus (rAAV) gene therapy products.

This individual will be accountable for design and management of process development, characterization, and tech transfer of rAAV upstream manufacturing processes.


The Scientist will collaborate with internal and contract laboratories to support development of upstream processes and definition of an AAV production platform for UCB's gene therapy offerings.


Who you'll work with:

What you'll do:

  • Collaborate with internal crossfunctional laboratories and external CDMOs.
  • Draft and execute bioreactor and shake flask cell culture studies for development of processes supporting First in Human studies through commercialization for rAAV gene therapy products.
  • Author & review technical documents including process descriptions, study designs, SOPs, technical position papers, & technical reports.
  • Identify & evaluate new technologies to improve and refine rAAV production platforms.

Interested? For this role we're looking for the following
education, experience
and
skills

  • Academical background in Chemical Engineering, Bioengineering, Biology, Biochemistry, Virology or related fields with
    experience in Process Development of large molecule or cellular therapies:
  • 2 years of experience (PhD)
  • 4 years of experience (Master)
  • 6 years of experience (Bachelor)
  • Technical knowledge and experience with stirred tank bioreactor operation and process development including scaleup/scaledown principles.
  • Knowledge of
    cGMP manufacturing guidance and experience with technical investigations and root cause analysis.
  • Experience with data and statistical analysis.
  • Interpersonal skills to communicate and maintain good working relationship with internal and external customers.
  • Very good command in English, both spoken and written.
Are you ready to 'go beyond' to create value and make your mark for patients? If this sounds like you, then we would love to hear from you

About us
UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 8,500 people in all four corners of the globe, inspired by patients and driven by science.

Why work for us?
At UCB, we don't just complete tasks, we create value. We aren't afraid to push forward, collaborate, and innovate to make our mark for patients.

We have a caring, supportive culture where everyone feels included, respected and has equitable opportunities to do their best work.

We 'go beyond' to create value for our patients, and always with a human focus, whether that's on our patients, our employees or our planet.

Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential.


Learn more about sustainability at UCB and how it is integrated into our business approach.

UCB and its subsidiaries encourage diversity and inclusion in the workplace; we are an Equal Opportunity Employer. We do not discriminate on the basis of race/colour/religion/sex/national origin/veteran/disability/age/sexual orientation/gender identity.

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