Towards an innovative strategy to bioprint a tooth
il y a 1 mois
Despite today's technological advancements and professional health care, tooth loss remains a global health problem. The tooth is a complex structure composed of the highly mineralized tissues (enamel and dentin) enclosing a soft vascularized tissue, the dental pulp. As the teeth and dental tissues cannot regenerate, missing teeth need to be replaced. Current dental restoration solutions are made of synthetic materials and are prone to mechanical and biological failure. Hence, there is an urgent need to new strategies, preferentially made of human biological materials.
The ultimate goal of this project is to bioprint a 3D tooth. Specifically, we will bioprint a structure composed of human cells, that mimics the anatomy of the human tooth, hence composing of three layers: enamel, dentin and soft dental pulp. First, we will design three different spheroidical building blocks composed of human cells: enamel, dentin and vascularized pulp spheroids. Next we will optimize a bio-ink and use these building blocks together with novel bioprinting techniques to print 3D tooth constructs. We will also evaluate whether the 3D constructs can be used to repair dental tissues and even totally replace a tooth using rat models. This project will not only pave the way for cell-based tooth regeneration strategies in the clinic but the developed bioprinting strategies can also be applied for other tissue regeneration purposes such as cartilage and bone.The succesful candidate will conduct PhD research under the supervision of Prof. Heidi Declercq (KU Leuven) and Prof. Annelies Bronckaers (UHasselt). You will play an active role in the research team, take part in workshops, conferences and other activities. You will be based at KU Leuven Campus Kulak (Kortrijk), Department of Development and Regeneration of KU Leuven.You will benefit from an established infrastructure for research and join the Tissue Engineering Lab in Kortrijk. You will have access to specialized training courses and the opportunity to present your research at national and international conferences.We offer a doctoral position for 1 year in an interdisciplinary environment. After a positive evaluation, the position is prolonged with 3 years.You will have access to state-of-the-art research facilities (bioprinter, light-sheet microscopy, flow cytometry,...) and will be registered in a specific program of the doctoral school.You will have active collaborations with (inter)national laboratories.You will work in a stimulating, international research environment in an academic laboratory.
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Towards an innovative strategy to bioprint a tooth
il y a 2 semaines
Kortrijk, Flandre, Belgique KU Leuven Temps pleinYou must hold a Masters' degree in biomedical sciences, biomedical engineering, bioengineering, pharmaceutical sciences, or equivalent related fields.You have experience with general laboratory skills, microscopy, cell culture,...You should have solid knowledge of tissue engineering, histology, biology,...You should be a team player with good oral and...
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Regulatory Officer
il y a 1 semaine
Kortrijk, Belgique Barco Temps plein**Date**:Mar 8, 2024 **Location**: Kortrijk, BE **Company**:Barco **Main accountabilities** As a regulatory Officer, you will be setting the regulatory framework and strategy by developing global regulatory pathways to bring new Medical Devices and Medical software to market. You will be engaged in the full lifecycle of the products and software. You...
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il y a 4 semaines
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il y a 2 semaines
Kortrijk, Flandre, Belgique Barco Temps pleinDate:Mar 8, 2024Location: Kortrijk, BECompany:BarcoMain accountabilitiesAs a regulatory Officer, you will be setting the regulatory framework and strategy by developing global regulatory pathways to bring new Medical Devices and Medical software to market. You will be engaged in the full lifecycle of the products and software.You will evaluate global...
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Product Lead Cinema
il y a 2 semaines
Kortrijk, Flandre, Belgique Barco Temps pleinBarco, a pioneering force in visualization and collaboration technology, leads the global market with innovative solutions tailored for the entertainment, healthcare, and enterprise sectors. Barco Cinema champions cutting-edge advancements such as laser projection, HDR technology, and comprehensive services that elevate the cinematic experience for...
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il y a 4 semaines
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Product Lead Cinema
il y a 4 semaines
Kortrijk, Belgique Barco Temps pleinBarco, a pioneering force in visualization and collaboration technology, leads the global market with innovative solutions tailored for the entertainment, healthcare, and enterprise sectors. Barco Cinema champions cutting-edge advancements such as laser projection, HDR technology, and comprehensive services that elevate the cinematic experience for...
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il y a 2 semaines
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il y a 1 mois
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il y a 1 semaine
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il y a 1 mois
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il y a 2 semaines
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