2 Erc-funded Postdoctoral S Focusing On Therapeutic

il y a 4 semaines

Gent, Belgique VIB Temps plein

Posted Date
- 05 Feb 2024
- Locations
- Ghent
- Center
- VIB-UGent Center for Inflammation Research
- Lab
- Roos Vandenbroucke Lab
- Type
- Post-doctoral
- Positions
- 2

**Job description**:
We're offering two postdoctoral positions funded by an ERC project aimed at revolutionizing therapeutic delivery into the brain via the blood-CSF barrier. Our pioneering research harnesses the power of single-domain antibodies, also known as nanobodies or VHHs, as a Trojan horse for targeted brain delivery. Our goal is to explore the vast potential of VHHs in effectively transporting diverse cargos -ranging from proteins to nucleic acids and nanoparticles

**Profile**:
You will become an integral part of a subteam, collaborating with an experienced lab technician and a dedicated PhD student whose project focuses on _in vitro_ screening methods, using a.o. organoids. We are looking for individuals with expertise in the following specific profiles to enhance and complement the team:
**Profile 1**

Ph.D. in Pharmaceutical sciences or related fields.

Demonstrated expertise in:

- Drug delivery.

**Profile 2**

Ph.D. in Molecular biology or related fields.

Demonstrated expertise in:

- _ In vitro_ and/or _in vivo_ phage display;
- Cloning, engineering, expression, purification and characterization of VHHs.

Join us to undertake a highly innovative project that combines cutting-edge approaches including state-of-the-art imaging techniques, pluripotent stem cell models, _in vivo_ mouse models of neurological disorders, drug (brain) delivery and nanobody development.

**We offer**:

- A state-of-the-art laboratory environment.
- A versatile and challenging academic position with very diverse contacts in a world-class research environment operating at an international level, and various opportunities to broaden your expertise.
- Opportunities to train in many cutting-edge technologies.
- Training courses in academic, technical, and career skills.
- A competitive salary and a range of benefits including a bicycle allowance and eco vouchers.
- An initial 1-year contract, which can be extended up to 5 years.

Starting Date: as soon as possible.

**How to apply?**:

- a 1-page summary of your motivation for the position, your research experiences and future goals
- a detailed CV including publication list
- contact information of 2-3 references

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