Phd Position at The Computational Neurobiology Lab

il y a 1 semaine

Antwerpen, Belgique VIB Temps plein

**PhD Position: Novel single-cell technology for detection of regulatory chromatin interactions and network inference of fate trajectories in adult neural stem cells**:
The Computational Neurobiology Lab at the VIB Center for Molecular Neurology is looking for a full-time (100%) doctoral scholarship holder in the fields of molecular and computational neurobiology.

**Position**:

- You will join our vibrant team to work on a challenging and exciting project at the intersection of **genetics, epigenetics, computational biology and neuroscience with a specific focus on adult neurogenesis. **Adult neurogenesis in the dentate gyrus (DG) plays an essential role in normal cognitive function, including memory formation, learning, pattern separation and mood regulation. Adult neurogenesis is vital for brain repair following traumatic brain injury and is disrupted in neurodegenerative disorders. In the DG, neural stem cells (NSCs) transition from a quiescent to an active state, giving rise to neural intermediate progenitor cells which then go on to produce neuroblasts and ultimately new neurons. The molecular mechanisms underlying such state transition remain poorly understood. We hypothesise that quiescent NSCs exist in distinct states, distinguishable at the level of chromatin states and 3D chromatin organisation, and that changes in chromatin organisation coordinate the transition from quiescence to self-renewal. This project aims to investigate this hypothesis using a combination of state-of-the-art experimental omics technologies and integrative computational approaches.
- You will write several scientific articles on this research project and present your work at national and international conferences.
- You will contribute to other research directions in the lab.
- You will carry out several teaching (from the 3rd year) and research support tasks at the University of Antwerp.

**Profile**:
**Required qualifications and must-have skills**
- You hold (or will have obtained by the start date) a master’s degree in genetics, neurobiology, systems biology, molecular biology or related disciplines.
- You can demonstrate excellent academic results
- You have solid knowledge of molecular and cellular processes involved in neurogenesis
- You have deep understanding of gene regulatory mechanisms underlying cell fate acquisition and maintenance
- You are confident in basic molecular biology techniques
- You are very motivated to learn and expand both computational and experimental skill set
- You have analytical mindset
- You have excellent communication and writing skills in English
- You act with attention to quality, integrity, creativity and cooperation.

**Desired skills**
- You understand the theory behind and have hands-on experience with single-cell data processing and multimodal data generation
- You have intermediate programming skills in R and/or python

**What we offer**:

- A doctoral scholarship for a period of 2 years (2025-2027). Following a positive evaluation, the scholarship can be renewed for another 2 years (2027-2029).
- You will become part of our vibrant enthusiastic international lab and supportive community at the VIB CMN, University of Antwerp, as well as VIB Center for AI and Computational Biology, with which our lab is affiliated.
- You will get access to numerous training courses at the UA and VIB.
- You will receive eco-cheques, an Internet-connectivity allowance, and a bicycle allowance or a full reimbursement of public transport costs for commuting.
- You will do most of your work at the Campus Drie Eiken in a dynamic and stimulating working environment.

**Want to apply?**:

- **a motivation letter** (1-2 pages), clearly addressing each of the following points:

- why you are particularly interested in this research project and how it aligns with your academic and career goals
- any relevant knowledge or experience you have in the fields of neuroscience, systems biology, or related disciplines
- your understanding of key challenges or open questions within the field of adult neurogenesis that you find particularly exciting
- **your academic CV** (1-2 pages), clearly specifying:

- mastered experimental and computational skills
- publications (if any)
- contact information of two **referees**.

While longer letters are acceptable, we strongly encourage concise, well-structured letters that clearly communicate your knowledge, interest and fit for the project. Quality and focus are preferred over length.

  • Postdoctoral Position in The Lab of Computational

    il y a 4 semaines

    Antwerpen, Belgique VIB Temps plein

    **Project description**: The Computational Neurobiology lab studies causal mechanisms underlying normal and aberrant cellular decision-making in the human brain in health and neurodegenerative diseases. We investigate the role of spatial chromatin organization in cell fate acquisition and maintenance, using a variety of targeted and genome-wide profiling...

  • Phd Position in Molecular and Computational

    Il y a 5 mois

    Antwerpen, Belgique VIB-UAntwerp Center for Molecular Neurology Temps plein

    **Project description**: We are a highly motivated international team of researchers at the Molecular Neurogenomics group (Jordanova Lab) and the Computational Neurobiology group (Malysheva Lab) at the VIB CMN. We are excited to announce a call for a joint Ph.D. student in our labs to work on a challenging project at the interface of neurodegeneration,...

  • Phd Molecular and Computational Neurogenomics

    Il y a 5 mois

    Antwerpen, Belgique Universiteit Antwerpen Temps plein

    Niet gevonden wat je zocht? Sla je zoekopdracht dan op en maak een job alert aan op de online sollicitatiemodule om automatisch op de hoogte te blijven van interessante toekomstige vacatures. Meer informatie kan je hier vinden. Departement: Faculteit Farmaceutische, Biomedische en Diergeneeskundige Wetenschappen Regime Voltijds **Let’s shape the future -...

  • Phd Position in Molecular and Computational

    Il y a 2 mois

    Antwerpen, Belgique VIB Temps plein

    **Project description**: We are a highly motivated international team of researchers at the Molecular Neurogenomics group (Jordanova Lab) and the Computational Neurobiology group (Malysheva Lab) at the VIB CMN. We are excited to announce a call for a joint PhD student in our labs to work on a challenging project at the interface of neurodegeneration,...

  • Senior Researcher or Postdoc in The Lab of

    il y a 2 semaines

    Antwerpen, Belgique Universiteit Antwerpen Temps plein

    Niet gevonden wat je zocht? Sla je zoekopdracht dan op en maak een job alert aan op de online sollicitatiemodule om automatisch op de hoogte te blijven van interessante toekomstige vacatures. Meer informatie kan je hier vinden. **Van vrijdag 15 november, 17u tot en met maandag 18 november 2024 is het niet mogelijk om online te solliciteren of je...

  • Doctoral scholarship holder molecular and computational neurobiology

    il y a 1 jour

    Antwerpen, Belgique Karlstad University Temps plein

    Doctoral scholarship holder molecular and computational neurobiology Let’s shape the future - University of Antwerp The University of Antwerp is a dynamic, forward-thinking, European university. We offer an innovative academic education to more than 20000 students, conduct pioneering scientific research and play an important service-providing role in...

  • Doctoral Scholarship Holder in The Field of

    Il y a 5 mois

    Antwerpen, Belgique Universiteit Antwerpen Temps plein

    Niet gevonden wat je zocht? Sla je zoekopdracht dan op en maak een job alert aan op de online sollicitatiemodule om automatisch op de hoogte te blijven van interessante toekomstige vacatures. Meer informatie kan je hier vinden. Departement: Centrum voor Moleculaire Neurologie Regime Voltijds **Let’s shape the future - University of Antwerp** The...

  • Postdoc Position in The Laboratory for

    il y a 2 semaines

    Antwerpen, Belgique VIB Temps plein

    The Laboratory for Gut-Immune-Brain Axis Research at the VIB-Center for Molecular Neurology is a newly established and expanding research group led by Dr. Sebastiaan De Schepper. The lab focuses on how the peripheral immune system shapes the brain immune landscape in health and disease, with a particular emphasis on tissue-resident macrophages along the...

  • Lab Technician

    il y a 3 semaines

    Antwerpen, Belgique Universiteit Antwerpen Temps plein

    Niet gevonden wat je zocht? Sla je zoekopdracht dan op en maak een job alert aan op de online sollicitatiemodule om automatisch op de hoogte te blijven van interessante toekomstige vacatures. Meer informatie kan je hier vinden. Departement: Centrum voor Moleculaire Neurologie Regime Voltijds **Let’s shape the future - University of Antwerp** The...

  • Phd Position in The Area of Quantitative in Situ

    il y a 6 jours

    Antwerpen, Belgique Universiteit Antwerpen Temps plein

    Niet gevonden wat je zocht? Sla je zoekopdracht dan op en maak een job alert aan op de online sollicitatiemodule om automatisch op de hoogte te blijven van interessante toekomstige vacatures. Meer informatie kan je hier vinden. Departement: Departement Fysica Regime Voltijds **Let’s shape the future - University of Antwerp** The University of Antwerp is...

  • Bell Labs Internship

    Il y a 6 mois

    Antwerpen, Belgique NOKIA Temps plein

    **Come create the technology that helps the world act together** Nokia is committed to innovation and technology leadership across mobile, fixed and cloud networks. Your career here will have a positive impact on people’s lives and will help us build the capabilities needed for a more productive, sustainable, and inclusive world. We challenge ourselves...

  • Lab Technician

    Il y a 2 mois

    Antwerpen, Belgique Universiteit Antwerpen Temps plein

    Niet gevonden wat je zocht? Sla je zoekopdracht dan op en maak een job alert aan op de online sollicitatiemodule om automatisch op de hoogte te blijven van interessante toekomstige vacatures. Meer informatie kan je hier vinden. Departement: Centrum voor Moleculaire Neurologie Regime Voltijds **Let’s shape the future - University of Antwerp** The...

  • Phd Position Quantitative in Situ Electron

    Il y a 5 mois

    Antwerpen, Belgique Universiteit Antwerpen Temps plein

    Niet gevonden wat je zocht? Sla je zoekopdracht dan op en maak een job alert aan op de online sollicitatiemodule om automatisch op de hoogte te blijven van interessante toekomstige vacatures. Meer informatie kan je hier vinden. Departement: Departement Fysica Regime Voltijds **Let’s shape the future - University of Antwerp** The University of Antwerp is...

  • Lab Technician

    il y a 1 mois

    Antwerpen, Belgique VIB Temps plein

    **Description**: The laboratory of Neuroimmunology (NIM), headed by Prof. Dr. Emanuela Pasciuto, is a part of the VIB-Center for Molecular Neurology (CMN) and focuses on multiple aspects of T cells biology in the context of neuropathology. We are looking for a lab technician who will join the team and provide hands-on support in tasks related to mouse...

  • Phd Positions Quantitative in Situ Electron

    Il y a 6 mois

    Antwerpen, Belgique Universiteit Antwerpen Temps plein

    Niet gevonden wat je zocht? Sla je zoekopdracht dan op en maak een job alert aan op de online sollicitatiemodule om automatisch op de hoogte te blijven van interessante toekomstige vacatures. Meer informatie kan je hier vinden. Departement: Departement Fysica Regime Voltijds **Let’s shape the future - University of Antwerp** The University of Antwerp is...

  • Laboratory Technician

    il y a 3 semaines

    Antwerpen, Belgique VIB Temps plein

    The Laboratory for Gut-Immune-Brain Axis Research is a newly established and expanding research group led by Dr. Sebastiaan De Schepper. The lab focuses on how the peripheral immune system shapes the brain immune landscape in health and disease, with a particular emphasis on tissue-resident macrophages along the gut-brain axis. We use various transgenic...

  • Lab Planner

    Il y a 6 mois

    Antwerpen, Belgique Maandag Temps plein

    **Over de functie**: Als **Lab Planner **ben je deel van het Clinical Release and Stability team (CRS) dat meewerkt aan analytical development in therapeutische ontwikkeling en supply. Je bent verantwoordelijk voor het uitvoeren van planningsactiviteiten gerelateerd aan testings voor vrijgave, stabiliteit en karakterisering (chromatografie, dissolutie,...

  • Senior Scientist, Manufacturing Sciences

    Il y a 6 mois

    Antwerpen, Belgique Johnson & Johnson Temps plein

    The Scientist position will be based in the **small molecule drug substance **labs as part of Manufacturing Science and Technology (MSAT). The position supports a multi-functional team in developing and deliver solutions required to maintain continued supply of Johnson and Johnson innovative medicines. The position primarily supports the Life Cycle...

  • Manager, Lab Systems

    Il y a 5 mois

    Antwerpen, Belgique Johnson & Johnson Temps plein

    The J&J Innovative Medicine Supply Group, is recruiting for a manager Lab Systems, reporting into QC Operations. This position carries responsibility for: - eLIMS data management for Janssen site’s. Ensures on time & high quality of master data upload in LIMS for all Janssen activities. The eLIMS CoE has the responsibility to take the final quality...

  • Temporary Lab Assistant

    Il y a 2 mois

    Antwerpen, Belgique CBRE Temps plein

    **Temporary Lab Assistant** **Job ID** - 184605**Posted** - 25-Sep-2024**Service line** - GWS Segment**Role type** - Full-time**Areas of Interest** Facilities Management **Location(s)** Antwerp - Antwerpen - Belgium **For our client Galapagos in Mechelen we are looking for a temporary Lab Associate - for a remplacement of employee who will be in...