Senior Scientist, Manufacturing Sciences
Il y a 7 mois
The Scientist position will be based in the **small molecule drug substance **labs as part of Manufacturing Science and Technology (MSAT). The position supports a multi-functional team in developing and deliver solutions required to maintain continued supply of Johnson and Johnson innovative medicines. The position primarily supports the Life Cycle Management (LCM) portfolio by performing lab-based activities in support of ongoing manufacturing as well as to tackle manufacturing issues.
You will be working in close collaboration with our partners in MSAT Innovation and technology department, R&D, and quality and will deliver the key data to support LCM activities.
You will have technical leadership and support responsibilities throughout the product life cycle. They will:
- develop, plan, lead and complete lab-based activities, mimicking full scale process performance, performing root cause analysis experiments, use-tests, or reprocess testing/development).
- transfer sophisticated processes, manufacturing technologies, analytical technologies to multiple sites and other laboratories.
- evaluate process and process analytical technology (PAT) data to define experimental activities to understand and resolve manufacturing issues.
- Lead or support process capability and quality improvement efforts on new or marketed products.
- Provide advanced expertise to assist in the implementation of technical transfers at internal and external manufacturing sites based on lab results and reduced scale process models.
**Qualifications**:
You should have excellent laboratory skills and research experience, with emphasis on:
- Experience with organic chemistry, chemical process development
- Use of electronic lab notebook systems and instrument logbooks
- Analysis and interpretation of data
- Experience with analytical tools (U/HPLC, GC, NMR)
- Experience with process analytical technologies (PAT) like FTIR, FBRM, Raman Spectroscopy would be highly desired.
- Experience with operational responsibilities of a laboratory, including purchasing materials, equipment set up/operation, management of chemicals, which may include controlled substances.
- Technical writing for the generation of technical reports
- experience with document control systems and change control systems is helpful or the willingness to learn
- Basic understanding of statistical methods and statistical process control.
- Understanding of good manufacturing practice (GMP).
- Ability to seek out and engage with various partners both globally and on-site.
- Laboratory safety practices and response procedures,
Holds a PhD or Master’s degree related to chemical manufacturing or has a Bachelor’s and extensive lab and manufacturing experience in process development or chemical / pharmaceutical production.
**Languages**:
Proficient in written and spoken English.
Proficiency in Dutch is an asset.
**Specific systems**:
Microsoft Office, Minitab, Lab Note book, Lab systems eg HPLC, GC
**Physical requirements/working conditions**:
Main location: Beerse/Geel
Works in an international environment across different time zones.
Travel: This position requires up to 10 % (domestic and international) travel.
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