Formulation Scientist
il y a 3 semaines
J&J Research & Development develops treatments that improve the health and lifestyles of people worldwide. R&D development areas encompass novel targets in neurologic disorders, gastroenterology, oncology, diabetes, hematology, metabolic disorders, immunologic disorders, pulmonary hypertension and reproductive medicine. Within Pharmaceutical Product Development & Supply (PPDS), we are recruiting a **Scientist **in the **Parenterals & Liquids Development **(PLD) department in Beerse, Belgium.
The PLD team is at the forefront of innovation, developing groundbreaking Parenteral and Liquid drug product formulations and processes across our R&D Synthetics portfolio (small molecules, peptides, oligonucleotides), from late Discovery to Commercialization. This portfolio covers a variety of formulation types such as solutions, microsuspensions, nanosuspensions, liposomes, biodegradable microspheres and injectable biodegradable rods. The team is exploring various administration routes including oral, IV, IM, SC, intra-organ, intra-tumoral, topical, nasal, ophthalmic, transdermal, intrathecal and inhalation.
**Tasks & Responsibilities**:
- Performs formulation and process development activities for innovative parenteral and liquid dosage forms across our R&D Synthetics portfolio, with strong focus on development of Long Acting Injectables. The development activities span from preclinical to clinical phases up to commercialization.
- Designs formulations, performs hands-on laboratory work and captures results in electronic lab notebook and reports.
- Provides input for master batch records for clinical batches. Performs criticality analysis assessments and defines control strategies.
- Writes source documents in support of regulatory filings and provides scientific responses to inquiries from Health Authorities.
- Develops expertise in assigned technical/scientific areas, reads relevant publications and patents, and actively looks for IP opportunities.
- Collaborates with various internal stakeholders such as Pharmaceutical & Material Sciences, Analytical Development, Pharmaceutical Supply & Engineering Sciences, Quality, Legal, Supply Chain and collaborates with external partners.
**Qualifications**:
- Ph.D. in Pharmaceutical Sciences/Chemistry/ Bioengineering/Chemical Engineering or Master's degree in these fields with minimum 7 years of relevant experience.
- Expertise in Parenterals & Liquids formulation and process development for synthetic drug compounds (small molecules, peptides, oligonucleotides), including expertise in Advanced Drug Delivery platforms such as Long Acting Injectables (nanosuspensions, biodegradable microspheres, injectable biodegradable rods, gels), Liposomes and Oral Peptide delivery. A background in aseptic/sterile processes, nanonization techniques and lyophilization is desired.
- Demonstrated strong innovation mindset, critical thinking capabilities and problem-solving attitude. Ability to evaluate and screen new dosage forms, manufacturing technologies and new Drug Delivery opportunities.
- Excellent team player with strong oral and written communication skills who thrives in a collaborative matrix environment. Ability to partner with external (academic) networks and CDMOs.
Our offer:
- An exciting position in an international and dynamic environment with continuous learning and growth opportunities
- Working on a site that harbors all aspects of the drug discovery and development process, located close to the vibrant city of Antwerp.
- A competitive salary, on-site sport accommodations, health/energy programs and other benefits for you and your family.
- An inclusive team environment where diversity and different opinions are respected and valued, and the importance of a good work-life balance is recognized.
Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
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