Associate Scientist

ppToday, precision medicine coupled with advanced diagnostics is taking over. However, those innovations in medicine come with an ever-increasing price tag driven by more expensive and complicated solutions making them less accessible unless we do something about it. /ppbSignatur Biosciences /b was established with the mission of making cutting-edge diagnostic tools accessible to more patients around the world. As a startup we have developed a technology to profile complex molecular signatures in a single reaction using qPCR machines already in place in every biomedical lab around the world. Signatur Biosciences is a startup with a remote workforce, predominantly in London, UK, and is establishing a new laboratory facility in Liège, Belgium. /ppWe're worried about accessibility in precision diagnostics and are building a team of individuals who share our passion for solving this problem through close collaboration and a sense of urgency. We're building a different kind of company, where employees think like owners, act with authority, and collaborate closely with one another. /ppWe are seeking a highly motivated and driven Senior Technical Assistant to join our team to help establish our new Belgium laboratory facility (full time, on site). In this role, under the direction of the Head of Laboratory Operations, you will be responsible for developing, implementing and maintaining all necessary procedures and process required for a state-of-the-art ISO13485 compliant laboratory facility and for the generation of data to support the development of next generation molecular diagnostic products. You will join Signatur Biosciences at an exciting time as we are a small start-up company looking to grow. You will be part of an expanding laboratory operations team but also interact with colleagues across the company who have the shared mission to make precision diagnostics more accessible. If you are a highly motivated and driven self-starter with a passion for novel diagnostics development, we'd love to speak with you /ppbAbout the role: /bAs an Associate Scientist, you will be responsible for conducting qPCR experiments in accordance with protocols and work instructions to support research, development and manufacturing activities. You will play a crucial role in advancing innovative diagnostic solutions by performing molecular biology techniques, analyzing experimental data, and ensuring the highest standards of quality and accuracy. /ph3Technical Expertise /h3pExpert in PCR /ppExperience with nucleic acid extraction /ppProven track record of timely and accurate laboratory record keeping /ppExperience in working collaboratively and coordinating laboratory activities /ph3Skills, Experience Attributes /h3pMinimum Bachelor or equivalent Science degree in biology, molecular biology, synthetic biology, bioengineering, or similar /ppAt least 3 years of hands-on molecular biology laboratory experience (not including course work) /ppExperience working within a Quality Management System for In Vitro Diagnostic development (ISO13485) /ppAI-augmented mindset: comfortable adopting AI tools to accelerate day-to-day tasks; genuinely curious about applying emerging AI capabilities to scientific and operational challenges /ppExperience in extraction of nucleic acid from FFPE blocks /ppPrevious start-up industry experience /ppExperience in using automated PCR set-up /ppExperience of working within biobanking requirements /ppExperience in writing study protocols following relevant international guidelines (e.g. CLSI) /ppMentoring and/or coaching team members /ph3Main

Responsibilities:
/h3h3People and Functional Development /h3pResponsible for adherence to laboratory procedures to ensure a safe and effective laboratory environment /ppAssist in the sourcing, storage, handling and maintenance of records with regards biological samples in accordance with the relevant requirements /ppBe responsible for adhering to the work instructions and training for specific laboratory processes/equipment as a lab process expert /ppContribute to the laboratory processes / procedures implementation in accordance with In Vitro Diagnostic development (ISO13485) /ppSupport the Head of Laboratory Operations in the implementation and monitoring of metrics (Key Performance Indicators) of laboratory efficiency effectiveness /ppContribute towards the continuous improvement and operations of Signatur Biosciences /ppTraining and coaching of laboratory team members /ph3Project and Product Delivery /h3pContribute to the efficient translation of study plans and protocols into detailed laboratory work instructions/worksheets to enable laboratory execution /ppConduct laboratory studies in accordance with work instructions and/or study protocols in support of research and/or product development projects including: /ppPerforming qPCR experiments manually or using high-throughput liquid handlers (for example i.
DOT machine) /ppCarry out nucleic acid extractions acco