Phd Student in Cancer Research

il y a 14 heures

Gent, Belgique VIB Temps plein

**More info on the PhD project**:
The new PhD student will work on a project that aims to obtain further understanding on the origin of nucleic acids that are shed in liquid biopsies, such as blood, using cancer models (mouse and rat) and patient samples of neuroblastoma disease, a rare childhood cancer. Nucleic acids in both tissue and liquid biopsy samples will be investigated. Examples of techniques that will be used in this PhD project include DNA/RNA isolation, DNA/RNA sequencing, spatial transcriptomics, qPCR, digital PCR, amongst others. Sequencing data analysis will be done using data analysis pipelines (Python, R) on the high-performance computing (HPC) infrastructure.

**About the TOBI lab**

**About VIB-UGent CMB & VIB.AI**:
The Center for Medical Biotechnology focuses on the development of new and innovative molecular tools and technologies to address human health problems. The center translates its insights to widely applicable research tools, vaccines, diagnostics, and biopharmaceuticals. The research at CMB pushes the boundaries of biomolecular and bioinformatics research and engineering technologies.

VIB.AI studies fundamental problems in biology by combining machine learning with in-depth knowledge of biological processes.

**Who we are looking for**:

- You have a Master in Science (Bioengineering, Biochemistry-Biotechnology, Biomedical Sciences, Medicine, or related).
- You have knowledge and insights in cancer biology and (epi)genomics.
- A Felesa C certificate allowing you to work in an animal lab (mouse and rat) is required.
- You have expertise with laboratory work in a molecular/genetic lab, including DNA- and/or RNA-sequencing technologies.
- Some expertise in bio-informatics and data-mining is a plus.
- You have analytical problem-solving skills, you are a team player, creative, critical, and open-minded.
- You have excellent oral and written communication skills in English.

**What we can offer you**:
You will work in a multidisciplinary environment under the supervision of senior scientists in the TOBI lab and within the broader framework of the Cancer Research Institute Ghent (crig.ugent.be). We offer:

- participation in an exciting and rapidly evolving research area of clinically translational genomics,
- being part of stimulating and supportive research teams operating at international level and dedicated to improve survival of patients with cancer,
- embedding within top-research teams with a broad range of expertise,
- access to state-of-the-art technology and facilities ((epi-)genomics, transcriptomics, (single-cell) sequencing, bioinformatics, etc),
- institutional training opportunities to broaden your expertise and skills.

**Interested?**:

- A cover letter, your CV
- Your diploma with the required degree (if already in your possession). If you have a foreign diploma in a language other than our national languages (Dutch, French, or German) or English, please add a translation in one of the mentioned languages.
- Optionally: one or more reference letters,

**More information**:

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