Biomarker Assay Development Lead

il y a 2 semaines

Gosselies, Belgique iTeos Therapeutics Temps plein

**ABOUT ITEOS THERAPEUTICS, INC**

iTeos Therapeutics is a publicly-traded (NASDAQ: ITOS), clinical-stage biopharmaceutical company dedicated to extending and improving the lives of patients with cancer by designing and developing next generation immunotherapies.

Based in Gosselies, Belgium and Watertown, MA, iTeos Therapeutics was founded out of the Ludwig Institute for Cancer Research (LICR) and the Duve Institute (UCLouvain) in 2011.

In March 2020, the Company completed a $125 million Series B2 financing, and in July 2020, we completed our IPO, raising over $230 million of gross proceeds. In June 2021, the Company entered into a transformative $2.145 billion co-development and co-commercialization agreement with GSK for EOS-448, the Company’s anti-TIGIT monoclonal antibody. As a well-capitalized biotech company, we are positioned to continue to develop our clinical pipeline and maintain our investments in our discovery research team to leverage our innovative science to improve the lives of patients with cancer.

**iTeos Therapeutics is now a world-class actor in the sector. To carry on its growth and reinforce its team, iTeos Therapeutics is looking for a**Biomarker Assay Development Lead**.**

**ROLE**:Biomarker Assay Development Lead**

To reinforce its Translational Medicine (TM) department, iTeos is looking for a highly motivated and creative scientific leader with strong expertise in developing, validating and implementing blood-based biomarker assays to be employed in cancer immunotherapy clinical trials.

**MAIN RESPONSIBILITIES**
- Shape and lead the newly created Biomarker Assay Development sub-team (1-2 research assistants).
- Lead the development of blood-based biomarker assays and other biological analyses, allowing the assessment of receptor occupancy, pharmacodynamic and pharmacokinetic activities for on-going clinical studies, in close interaction with the Biomarker Strategy team.
- Oversee the preparation, implementation and follow-up of all biological analyses for on-going clinical studies, in close interaction with the Biomarker Implementation team.
- Write/review biomarker sections of clinical documents in close interaction with the clinical teams, the biomarker leads and external service providers.
- Participate in the development of Biomarker and Precision Medicine enabling strategies and biomarker assay selection for diverse clinical-stage projects.
- Liaise with KOLs, academic institutes and external consultants to foster scientific excellence.
- Contributing to the growth and further development of the TM team.

**PROFESSIONAL EXPERIENCE/QUALIFICATIONS**
- PhD, MD/PhD in Cancer Immunotherapy, Immunology or Molecular Biology with a minimum of 2 years of relevant post-doctoral research experience in analyzing human samples and/or monitoring analysis of biomarkers generated from clinical trials.
- Direct experience with the discovery and characterization of biomarkers using flow cytometry, proteomics, molecular biology and possibly immunohistochemistry techniques. Experience with single cells technologies (ie scRNAseq, CyTOF) and/or multi-omics approaches (ie spatial omics, imaging mass cytometry) is a plus.
- Experience in qualification/validation, development, and outsourcing of clinically applicable biomarker assays, and analyzing corresponding data.
- Experience in implementing biological assays in clinical studies.
- Understanding of GCP/GCLP guidelines and current global regulations.
- Experience in drug development and clinical trial design and monitoring is desirable.
- Previous experience in Biotech/Pharma industry and oncology drug development is clearly a plus.
- Experience in people management a plus.
- Excellent English (oral and written), French is a plus.
- Solution-oriented, strong project, organization and problem-solving skills.
- Resilience with the ability to adapt to changes in priorities and to work effectively on multiple immune-oncology programs in a fast-paced environment.

**OFFER**
- A stimulating position within a high-potential innovative biotech company.
- The opportunity to work in a science-driven, dynamic, respectful, and professional environment.
- A challenging scientific and business growth in which you get to bring your knowledge and skills.
- An employment agreement contract with an attractive salary package in line with the position responsibilities and your experience.

**RECRUITMENT PROCESS

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