Gene Therapy Downstream Process Sciences Senior

il y a 3 semaines


Brainel'Alleud, Belgique UCB Temps plein

**Make your mark for patients**

We are looking for a **Gene Therapy Downstream Process Sciences Senior Scientist** who’s **dynamic, resilient and flexible** to join us in our **Gene Therapy Process Development** team, in **Belgium**

**About the role**

The **Gene Therapy (GT) Downstream Process Sciences Senior Scientist** will be responsible for **supporting Downstream Process Development activities for UCB’s recombinant adeno-associated virus (rAAV) gene therapy products**. This individual will be accountable for design and management of process development, characterization, and tech transfer of rAAV purification processes.

The Senior Scientist will collaborate with internal and external laboratories to support development of downstream processes and definition of an AAV production platforms and manufacturing facility requirements for UCB’s gene therapy offerings.

**What you’ll do**:

- Collaborate and present to cross-functional internal and external CMC technical teams.
- Design and execute chromatography and filtration studies for development of processes supporting First in Human studies through commercialization for rAAV gene therapy products.
- Author & review technical documents including CMC regulatory sections, process descriptions, study designs, SOPs, technical position papers, & technical reports.
- Identify, evaluate, and implement new technologies to improve and refine rAAV purification platforms.

**I**nterested? For this role we’re looking for the following** **education, experience** **and **skills***
- PhD or master’s degree in chemical engineering, bio engineering, biochemistry, virology or related disciplines.
- At least 6 to 8 years of industrial experience in Process Development of large molecules or cellular therapies.
- Excellent technical knowledge of biologics downstream manufacturing and process development (chromatography, TFF, NFF). Experience with rAAV manufacturing is desired.
- Knowledge of cGMP manufacturing guidance and experience with technical investigations and root cause analysis.
- Experience in Technical Project Leadership.
- Experience with data and statistical analysis.

Very good command in English, both spoken and written.

Are you ready to ‘go beyond’ to create value and make your mark for patients? If this sounds like you, then we would love to hear from you

**About us**
UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 8,500 people in all four corners of the globe, inspired by patients and driven by science.

**Why work for us?**
At UCB, we don’t just complete tasks, we create value. We aren’t afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected and has equitable opportunities to do their best work. We ‘go beyond’ to create value for our patients, and always with a human focus, whether that’s on our patients, our employees or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential.

**Learn more** about sustainability at UCB and how it is integrated into our business approach.

UCB and its subsidiaries encourage diversity and inclusion in the workplace; we are an Equal Opportunity Employer. We do not discriminate on the basis of race/colour/religion/sex/national origin/veteran/disability/age/sexual orientation/gender identity.



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