Gene Therapy Process Sciences Downstream

il y a 6 jours

Brainel'Alleud, Belgique UCB S.A. Temps plein

**Make your mark for patients.**

We’re here because we want to build the future and transform patients’ lives for the better. To achieve that, we need the brightest minds and biggest hearts. That’s why our Talent Acquisition Team looks for passionate people inside and outside the company. Are you interested in an internal move that will allow you to explore how much more you can do to make a difference for people living with severe disease?

To strengthen our new **Gene Therapy Bioprocess Development Department**, based in **Braine, Belgium** we are looking for a talented individual to fill the position of**:Gene Therapy Process Sciences Downstream (Associate) Scientist (With Structural Biology Background)**

The **Gene Therapy Process Sciences Downstream (Associate) Scientist (With Structural Biology Background)** will be responsible for **supporting **Downstream** **P**rocess **D**evelopment activities for UCB’s recombinant adeno-associated virus (rAAV) gene therapy products**. This individual will be accountable for design and execution of process development, characterization, and tech transfer of rAAV purification processes.

The (Associate) Scientist will collaborate with internal and external contract laboratories to support development of downstream processes and definition of an AAV production platform for UCB’s gene therapy offerings.

**Y**ou** **will more precisely **contribute** by**:

- Independently design and execute experiments while seeking inputs from peers.
- Analyze, document and present regularly with a focus on problem-solving to downstream team members.
- Develop an understanding of AAV physical and chemical properties to improve downstream purification process.
- From a wholistic point of view, assess risk and error deviations from all process aspects regardless of technology and operation constrain.
- Innovate and build our knowledge base on AAV process technologies.
- Collaborate with internal cross-functional laboratories and external CDMOs.
- Author & review technical documents including process descriptions, study designs, SOPs, technical position papers, & technical reports.
**I**nterested? For this position you’ll need the following** **education, experience** **and **skills**:

- PhD (Structural Biology or related fields) with 0-2 years of experience in the expression and purification of large molecule.
- Strong scientific understanding on fundamentals of biological entities (virus, proteins, DNA, etc) and interfacial sciences.
- Experience with molecular dynamics simulation.
- Knowledge of python or other programming languages.
- Technical knowledge of chromatography and/or membrane filtration.
- Hands-on experience with analytical instrumentation and method development.
- Experience with data and statistical analysis.
- Very good command in English, both spoken and written. Additional language skills in French is highly preferred but not required.
- Because collaborating with each other is key at UCB, we consider personality skills as important as the scientific background and knowledges. Therefore, we hope to complete our multicultural and dynamic team with someone **innovative** and **creative thinking** who likes to develop his/her **network** with **enthusiasm** and **passion**.
**Why you should apply**

At UCB, we strive to attract passionate and outstanding talents who thrive on change and are ready to bring real value to patients. Working for us you’ll discover a place where you can grow and express your full potential. We place an emphasis on innovation, collaboration and impact. Through meaningful recognition and a motivating work atmosphere, we aim to provide an optimal experience by caring about and valuing our employees - just as we do for the patients we serve.

**About us.**

UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are around 7,600 people in all four corners of the globe, inspired by patients and driven by science.

At UCB, everything we do start with a simple question: “How will this create value for people living with severe disease?”. We are on a journey to become the patient-preferred biopharma leader by delivering medicines and solutions that improve lives. We want to ensure the creation of patient value, now and into the future, while contributing to a society where a population of 8 billion people and more should be able to live a good life within limited resources of one planet.

UCB and its subsidiaries encourage diversity and inclusion in the workplace; we are an Equal Opportunity Employer. We do not discriminate on the basis of race/color/religion/sex/national origin/veteran/disability/age/sexual orientation/gender identity.

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