Phd or Post-doc in Molecular Biophysics
il y a 1 semaine
**About VIB - About the Center/Lab**:
VIB is a research institute spread over six university campuses in Flanders that aims to strengthen the excellence of Flemish life sciences research and to turn the results into new economic growth.
Within VIB, the **VIB-VUB Center for Structural Biology** is located on the Brussels campus of the Vrije Universiteit Brussel and hosts 10 PIs with varying expertise but all studying the structure-function relationships of proteins and macromolecular complexes.
The **Loris lab** combines structural biology and molecular biophysics to study questions about protein function and regulation, including mechanisms that depend on intrinsic disorder and dynamics-mediated allostery. One of the topics in the lab focusses on SOG1, a central regulator in DNA damage response. SOG1 is the plant equivalent of p53 and controls hundreds of genes. The underlying mechanisms are largely unknown, but likely involve phosphorylation of the IDP domain of SOG1 as well as the involvement of a number of as yet unidentified interaction partners.
**Job description**:
You will be working on a project that aims to unravel the relationship between liquid-liquid phase separation, intrinsic disorder, DNA binding and transcription activation for the NAC family of plant-specific transcription factors. For this project, the loris lab closely relates with the plant cell cycle group of Prof. Lieven De Veylder at the VIB-UGent Center for plant systems biology that supports us with its expertise in plant work.
**Profile**:
**Essential**
- For a prospective PhD student: Master in Bio-engineering sciences, (Molecular) biology, Biochemistry, Biotechnology or related, recently obtained (no more than one year) with at least the mention of distinction/cum laude.
- For a prospective post-doc: experience in protein chemistry, molecular biophysics including LLPS and/or structural biology is essential.
- You are fluent in English, both spoken and written.
**Desirable but not required**
- Experience with LLPS
- Experience with _in planta_ work and microscopy
- You are currently in the last year of your master/PhD studies or you have graduated in 2024
- Knowledge of the Dutch language will provide you with an advantage
**Key personal characteristics**
- You are highly communicative
- You enjoy collaborating with colleagues and function well in a team
- At the same time you can take initiative and work independent
**We offer**:
- A four year PhD or post-doc contract
- A working climate where trust, (international) collaboration, and commitment are essential
- Access to state-of-the art tools and infrastructure
- A stimulating and supportive international research environment
**How to apply?**:
Applications are expected on-line via jobsoid.
- A copy of your master/PhD diploma (unless it has not yet been obtained)
- A 1 page summary of your master/PhD thesis
- Only if available an English language certificate (will also be assessed during the interview)
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