Experienced Scientist Parenterals

il y a 2 jours


Antwerpen, Belgique Johnson & Johnson Temps plein

About Johnson & Johnson

Position overview

J&J Innovative Medicine Research & Development develops treatments that improve the health and lifestyles of people worldwide. R&D development areas encompass novel targets in neurologic disorders, gastroenterology, oncology, diabetes, hematology, metabolic disorders, immunologic disorders, pulmonary hypertension and reproductive medicine. Within Pharmaceutical Product Development & Supply (PPDS), we are recruiting an Experienced Scientist in the Parenterals & Liquids Development (PLD) department in Beerse, Belgium.

The PLD team is at the forefront of innovation, developing groundbreaking Parenteral and Liquid drug product formulations and processes across our R&D Synthetics portfolio (small molecules, peptides, oligonucleotides), from late Discovery to Commercialization. This portfolio covers a variety of formulation types such as solutions, (nano)suspensions, liposomes, lipid-based systems, biodegradable microspheres and injectable biodegradable rods. The team is exploring various administration routes including oral, IV, IM, SC, intra-organ, intra-tumoral, topical, nasal, ophthalmic, transdermal, intrathecal and inhalation.

Tasks & Responsibilities:

- Performs formulation and process development activities for innovative parenteral and liquid dosage forms across our R&D Synthetics portfolio.
- Designs formulations, performs hands-on laboratory work and captures results in electronic lab notebook and reports. Development activities span from preclinical to clinical phases.
- Develops expertise in assigned technical/scientific areas, searches the academic and patent literature to identify current best practices, gaps and IP opportunities relating to the scientific field, and translates new ideas into patient-centric solutions in support of drug development.
- Provides input for master batch records for clinical batches. Performs criticality analysis assessments and defines control strategies.
- Writes source documents in support of regulatory filings and provides scientific responses to inquiries from Health Authorities.
- Collaborates with various internal partners in Drug Development such as Pharmaceutical & Material Sciences, Analytical Development, Pharmaceutical Supply & Engineering Sciences, Quality, Legal, Supply Chain, and collaborates with external partners and CDMOs.

**Qualifications**:

- Ph.D. degree or Master’s degree with a minimum of 7 years of experience in a relevant field in Pharmaceutical Sciences / Chemistry / Bioengineering / Chemical Engineering.
- Demonstrated experience in parenterals and liquids formulation and process development for synthetic drug compounds (small molecules) with focus on long-acting / targeted release injectables and a good understanding of physical pharmacy and particle engineering principles. Experience in aseptic/sterile processes, milling and nanonization techniques, and lyophilization is desired.
- A background in advanced drug delivery technologies such as drug nanosuspensions, biodegradable microspheres, injectable biodegradable rods, gels, liposomes is advantageous.
- Scientific curiosity, innovation mentality, critical thinking capabilities and problem-solving inclination.
- Excellent teammate with strong oral and written communication skills who thrives in a collaborative environment. Ability to partner with external (academic) networks and CDMOs.
- Ability to conduct hands-on experiments accurately and safely in a modern laboratory environment.

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.


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