Principal Scientist in Vivo and Translational

Il y a 6 mois


Zwijnaarde, Belgique eTheRNA Temps plein

etherna provides research and manufacturing excellence by teaming up with highly skilled scientists, researchers and technical experts who are recognized for their contributions to the industry. We acquired substantial intellectual property and know-how over the years that support our exceptional leadership in mRNA and LNP innovation. With a careful balance in our skillset, state-of-the-art facilities and specialized equipment we tackle complex challenges and assure efficiency in our operations.**
***

**General job description**:
This position reports to the Director Pharmacology and is based at our research site in Zwijnaarde, Belgium.

**Responsibilities and Duties**:
The **Principal Scientist** ’s duties shall include, but not be limited to:Oversee in vivo pharmacology studies to established Proof of concept, mechanism of action, PK/PD, safety assessment and support lead selection for technology platform
- Prioritize workflow and follow challenging timelines of multiple projects to achieve project and company goals according to budget
- Coordinating activities with CROs when required
- Manage, mentor and develop scientists and staff
- Manage and review proper records in electronic notebook, peer-reviewing ELN entries and contribute to writing study report
- Contribute to the development of RNA and LNP delivery technology and the generation of intellectual property
- Present data internally, at scientific conferences and at meetings with partner organizations**Job requirements**:
**Education**:
PhD in immunology or toxicology with at least 6-8+ years’ experience of relevant experience in pharmaceutical or biotech industry

**Experience**:
- Experience driving in vivo and translational-safety pharmacology efforts and strategic planning of pharmacology packages path to support IND strategy is required.
- Understanding and experience in in vivo sciences/vivarium operations
- Experience in flow cytometry, ELISA, MSD, LC/MS, PCR-based methods is required
- Must have strong knowledge and/or experience with Pharmacokinetics assays, immunogenicity assays and toxicology to support non clinical studies and safety assessment of nanomedicine (mRNA-LNP would be an advantage)
- Experience with outsourcing assays and oversight of CRO activities is required.
- Demonstrated ability to lead and mentor a team of research associates and scientists with a strong commitment to developing junior staff.
- **Other Qualifications, Skills and Abilities**:
- Energetic and ambitious
- A strong team player
- Goal
- and timeline-oriented work
- High quality awareness
- Well-developed communication skills
- Proactive and flexible mindset who fosters innovation
- Capability to work in a highly dynamic environment
- Strong interpersonal skills that enable communication, collaboration and ability to effectively influence in matrix environment
- Proficiency in English**Our offer**:
- An exciting job in a dynamic and enterprising environment with room for initiative and personal development.
- Working within an innovative environment where you can learn a lot and take on responsibilities
- Employment contract of indefinite duration with a competitive salary package.
- Working in a fun team where collaboration, growth but above all fun are central



  • Zwijnaarde, Belgique Confo Therapeutics Temps plein

    Confo Therapeutics is the only GPCR company with a discovery engine that precisely targets desired GPCR **confo**rmations. This unique capability allows us to unlock a vast untapped potential for the discovery and development of breakthrough medicines. We are advancing a robust pipeline of large and small molecules focused on validated targets in endocrine...


  • Zwijnaarde, Belgique eTheRNA Temps plein

    etherna provides research and manufacturing excellence by teaming up with highly skilled scientists, researchers and technical experts who are recognized for their contributions to the industry. We acquired substantial intellectual property and know-how over the years that support our exceptional leadership in mRNA and LNP innovation. With a careful balance...


  • Zwijnaarde, Belgique eTheRNA Temps plein

    eTheRNA immunotherapies was founded in 2013. eTheRNA has established an integrated set of proprietary capabilities for an end-to-end solution to design, develop and manufacture next-generation mRNA products based on enabling technologies. eTheRNA’s business model will utilize this suite of capabilities to provide superior products for partners in both...


  • Zwijnaarde, Belgique Wolfson Recruitment Temps plein

    **RESEARCH SCIENTIST | INNOVATIEVE SPELER | 75K + PACKAGE**: - Status: open20/08/2024 Zwijnaarde - RESEARCH SCIENTIST | INNOVATIEVE SPELER | 70K + PACKAGE Een toonaangevend Belgisch onderzoekscentrum voor de textielindustrie is op zoek naar een gemotiveerde en ervaren Research Scientist voor de vestiging in Kortrijk. Dit centrum speelt een cruciale rol in...


  • Zwijnaarde, Belgique Eastman Temps plein

    **This is the role**: **This position is based in our European Technology Center in Ghent - Zwijnaarde en requires on-site presence** **Typical tasks and responsibilities are**: - Complying and promoting the Eastman Safety Culture and follow the safety rules applicable to our Analytical and.Material Characterization Laboratories. Maintaining a clean work...


  • Zwijnaarde, Belgique FOx Biosystems Temps plein

    **Vacancy: Research associate** After the opening of the FOx BIOSYSTEMS Innovation Lab, our brand new R&D facility near Ghent, we want to grow our biosensor and assay development team. We are now looking for a: **Research Associate** **Responsibilities**: - Contribute to the design of laboratory experiments. - Write, review, and maintain experimental...


  • Zwijnaarde, Belgique Eastman Temps plein

    **This is the role**: The position is based in the European Technology Center Ghent - Zwijnaarde (Belgium) Travel requirements 10 -30 % mostly within EU **Typical duties are**: - Develops and maintains a network with independent institutions and with the technical centers of key companies in the home and personal care industry. Actively participate in...


  • Zwijnaarde, Belgique Eastman Temps plein

    **This is the role**: We are currently seeking a highly skilled and motivated R&D Manager to join our dynamic team in our European Technology Center in Ghent (Zwijnaarde). The R&D manager will play a pivotal role in driving innovation and leading the development of new chemical products and technologies. Key responsibilities include: - Attracting,...


  • Zwijnaarde, Belgique Daikin Europe HQ Temps plein

    Daikin Europe NV (DENV) is a subsidiary of Daikin Industries Limited, a Japanese outstanding company and worldwide the biggest developer, producer and supplier of HVAC-R (heating, ventilation, air conditioning and refrigeration) solutions, including heating pumps and cooling technology. DENV is Daikin’s sales, R&D, and production headquarters for Europe,...


  • Zwijnaarde, Belgique Start People Gent (Orban) Temps plein

     DescriptionOur client is seeking a temporary Maintenance & Engineering Support Technician to join the CAR-T Asset Management team within Technical Operations. This role will involve supporting Commissioning and Qualification (C&Q) activities for the cGMP Clinical and Commercial Cell Therapy Manufacturing plants in Ghent.What can you expect from this...


  • Zwijnaarde, Belgique Confo Therapeutics Temps plein

    Confo Therapeutics is the only GPCR company with a discovery engine that precisely targets desired GPCR **confo**rmations. This unique capability allows us to unlock a vast untapped potential for the discovery and development of breakthrough medicines. We are advancing a robust pipeline of large and small molecules focused on validated targets in endocrine...


  • Zwijnaarde, Belgique Confo Therapeutics Temps plein

    Confo Therapeutics is the only GPCR company with a discovery engine that precisely targets desired GPCR **confo**rmations. This unique capability allows us to unlock a vast untapped potential for the discovery and development of breakthrough medicines. We are advancing a robust pipeline of large and small molecules focused on validated targets in endocrine...


  • Zwijnaarde, Belgique Confo Therapeutics Temps plein

    Confo Therapeutics is the only GPCR company with a discovery engine that precisely targets desired GPCR **confo**rmations. This unique capability allows us to unlock a vast untapped potential for the discovery and development of breakthrough medicines. We are advancing a robust pipeline of large and small molecules focused on validated targets in endocrine...


  • Zwijnaarde, Belgique Sirris Temps plein

    As the innovation companion for the technological industry, Sirris is the trusted reference for technology adoption in Belgium. We help companies to realise their innovation ambitions with hands-on support. At the heart of our services stand over 150 multi-disciplinary experts and a broad set of industrial labs spread over 8 Belgian sites, backed by the...

  • Ai Trainer

    il y a 8 heures


    9052 Zwijnaarde, Belgique Outlier Temps plein

    Outlier aide les entreprises les plus innovantes au monde à améliorer leurs modèles d'IA en fournissant des retours humains. Êtes-vous un rédacteur expérimenté en français belge qui souhaiterait mettre son expertise au service de la formation de modèles d'IA ? À propos de l'opportunité : Outlier recherche des rédacteurs talentueux,...

  • Moniteur sportif étudiant

    il y a 8 heures


    9052 Zwijnaarde, Belgique Outlier Temps plein

    Outlier aide les entreprises les plus innovantes au monde à améliorer leurs modèles d'IA en fournissant des retours humains. Êtes-vous un rédacteur expérimenté en français belge qui souhaiterait mettre son expertise au service de la formation de modèles d'IA ? Outlier recherche des rédacteurs talentueux, maîtrisant parfaitement le français...

  • Development Project Lead

    Il y a 6 mois


    Zwijnaarde, Belgique Confo Therapeutics Temps plein

    Confo Therapeutics is the only GPCR company with a discovery engine that precisely targets desired GPCR **confo**rmations. This unique capability allows us to unlock a vast untapped potential for the discovery and development of breakthrough medicines. We are advancing a robust pipeline of small molecules and antibody-based therapeutics focused on validated...


  • Zwijnaarde, Belgique Eastman Temps plein

    **This is the role**: **This position is based in our European Technology Center in Ghent - Zwijnaarde en requires on-site presence** **Typical tasks and responsibilities are**: - Using general analytical techniques and instrumentation which is not limited to but includes: Rheometers (Rotational and/or DMA), Viscometers, Thermogravimetric analysis,...


  • Zwijnaarde, Belgique Daikin Europe HQ Temps plein

    Strategic Product Manager Entity: Daikin Europe HQ Job Category: Product management & strategic product roadmapping Location: Zwijnaarde, East Flanders, BE Daikin Europe NV is a subsidiary of the Japanese group Daikin Industries Ltd., a worldwide leader in HVAC-R (heating, ventilation, air conditioning and refrigeration) technology, such as heat pumps,...


  • Zwijnaarde, Belgique Daikin Europe HQ Temps plein

    Strategic Product Manager Entity: Daikin Europe HQ Job Category: Product management & strategic product roadmapping Location: Zwijnaarde, East Flanders, BE Daikin Europe NV is a subsidiary of the Japanese group Daikin Industries Ltd., a worldwide leader in HVAC-R (heating, ventilation, air conditioning and refrigeration) technology, such as heat pumps,...