Principal Scientist in Vivo and Translational
Il y a 7 mois
etherna provides research and manufacturing excellence by teaming up with highly skilled scientists, researchers and technical experts who are recognized for their contributions to the industry. We acquired substantial intellectual property and know-how over the years that support our exceptional leadership in mRNA and LNP innovation. With a careful balance in our skillset, state-of-the-art facilities and specialized equipment we tackle complex challenges and assure efficiency in our operations.**
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**General job description**:
This position reports to the Director Pharmacology and is based at our research site in Zwijnaarde, Belgium.
**Responsibilities and Duties**:
The **Principal Scientist** ’s duties shall include, but not be limited to:Oversee in vivo pharmacology studies to established Proof of concept, mechanism of action, PK/PD, safety assessment and support lead selection for technology platform
- Prioritize workflow and follow challenging timelines of multiple projects to achieve project and company goals according to budget
- Coordinating activities with CROs when required
- Manage, mentor and develop scientists and staff
- Manage and review proper records in electronic notebook, peer-reviewing ELN entries and contribute to writing study report
- Contribute to the development of RNA and LNP delivery technology and the generation of intellectual property
- Present data internally, at scientific conferences and at meetings with partner organizations**Job requirements**:
**Education**:
PhD in immunology or toxicology with at least 6-8+ years’ experience of relevant experience in pharmaceutical or biotech industry
**Experience**:
- Experience driving in vivo and translational-safety pharmacology efforts and strategic planning of pharmacology packages path to support IND strategy is required.
- Understanding and experience in in vivo sciences/vivarium operations
- Experience in flow cytometry, ELISA, MSD, LC/MS, PCR-based methods is required
- Must have strong knowledge and/or experience with Pharmacokinetics assays, immunogenicity assays and toxicology to support non clinical studies and safety assessment of nanomedicine (mRNA-LNP would be an advantage)
- Experience with outsourcing assays and oversight of CRO activities is required.
- Demonstrated ability to lead and mentor a team of research associates and scientists with a strong commitment to developing junior staff.
- **Other Qualifications, Skills and Abilities**:
- Energetic and ambitious
- A strong team player
- Goal
- and timeline-oriented work
- High quality awareness
- Well-developed communication skills
- Proactive and flexible mindset who fosters innovation
- Capability to work in a highly dynamic environment
- Strong interpersonal skills that enable communication, collaboration and ability to effectively influence in matrix environment
- Proficiency in English**Our offer**:
- An exciting job in a dynamic and enterprising environment with room for initiative and personal development.
- Working within an innovative environment where you can learn a lot and take on responsibilities
- Employment contract of indefinite duration with a competitive salary package.
- Working in a fun team where collaboration, growth but above all fun are central
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